CRUNCH Results

QC summary table

QC statistics for this dataset

Comparison with ENCODE datasets

Mapping

Fraction of mapped reads for the IP samples:
0.788
59th percentile
Fraction of mapped reads for the background samples:
0.761
57th percentile

ChIP enrichment signal

Noise level ChIP signal:
0.245
`
70th percentile
Error in fit of enrichment distribution:
0.406
21st percentile

Peak statistics

Number of peaks:
19318
61st percentile
Fraction of reads mapped to peaks:
0.026
55th percentile

Motif enrichment statistics

Enrichment of top motif:
1.76
15th percentile
Enrichment of complimentary motif set:
3.21
10th percentile

Quality Control, Mapping, Fragment Size Estimation:

BCLAF Replicate 1

fragment size plot

BCLAF Replicate 2

fragment size plot

BG Replicate 1

fragment size plot

BG Replicate 2

fragment size plot

Peak Calling:

zvalue histogram reverse cumulative of zvalues

Top peaks:


Coordinates Z-score Nearest Genes on the Left Offset of Nearest TSS on the Left (Strand) Nearest Genes on the Right Offset of Nearest TSS on the Right (Strand) HCMC.ELF1_f1.wm HCMC.IRF8_si.wm ZNF143.p2 denovo_WM_17 HCMC.CTCF_f2.wm denovo_WM_21 HCMC.SPI1_si.wm JASPAR.Myf.wm HCMC.FOXM1_f1.wm
chr10:103124593..103124696 12.491 BTRC|beta-transducin repeat containing -10772 (+) POLL|polymerase (DNA directed), lambda 223285 (-)

chr14:35025372..35025563 12.490 EAPP|E2F-associated phosphoprotein -16582 (-) SNX6|sorting nexin 6 73888 (-)

chr14:35015953..35016144 12.461 EAPP|E2F-associated phosphoprotein -7163 (-) SNX6|sorting nexin 6 83307 (-)

chr17:19091361..19091525 12.361 GRAPL|GRB2-related adaptor protein-like -60662 (+) EPN2|epsin 2 49265 (+)

-30:0.293

29:0.283

chr17:18967212..18967403 12.164 GRAP|GRB2-related adaptor protein -17021 (-) GRAPL|GRB2-related adaptor protein-like 63474 (+)

59:0.293

0:0.283

chr17:8076704..8076895 11.858 VAMP2|vesicle-associated membrane protein 2 (synaptobrevin 2) -10507 (-) TMEM107|transmembrane protein 107 2861 (-)

chr1:45187349..45187540 11.566 C1orf228|chromosome 1 open reading frame 228 -47051 (+) KIF2C|kinesin family member 2C 18054 (+)

chr1:147511007..147511160 11.539 GPR89C|G protein-coupled receptor 89C -85517 (+) NBPF11|neuroblastoma breakpoint family, member 11 NBPF24|neuroblastoma breakpoint family, member 24 98997 (-)

chr15:65588392..65588576 11.523 PARP16|poly (ADP-ribose) polymerase family, member 16 -9324 (-) IGDCC3|immunoglobulin superfamily, DCC subclass, member 3 81867 (-)

58:0.256

chr1:145969276..145969426 11.495 GPR89C|G protein-coupled receptor 89C -85484 (+) NBPF11|neuroblastoma breakpoint family, member 11 NBPF24|neuroblastoma breakpoint family, member 24 98893 (-)

chr17:19093312..19093495 11.402 GRAPL|GRB2-related adaptor protein-like -62622 (+) EPN2|epsin 2 47305 (+)

72:0.293

12:0.283

chr17:18965367..18965537 11.332 GRAP|GRB2-related adaptor protein -15166 (-) GRAPL|GRB2-related adaptor protein-like 65329 (+)

45:0.509

chr22:50338926..50339103 11.289 CRELD2|cysteine-rich with EGF-like domains 2 -26639 (+) PIM3|pim-3 oncogene 15135 (+)

1:0.315, -42:0.315, 46:0.315, -86:0.315, 91:0.315

chr12:120729515..120729706 11.281 PXN|paxillin -26020 (-) SIRT4|sirtuin 4 10532 (+)

chr1:11968216..11968407 11.273 NPPB|natriuretic peptide B -49371 (-) KIAA2013|KIAA2013 18162 (-)

chr17:19015676..19015867 11.266 GRAP|GRB2-related adaptor protein -65485 (-) GRAPL|GRB2-related adaptor protein-like 15010 (+)

-93:0.509, 95:0.293

35:0.283

chr17:41438490..41438681 11.125 TMEM106A|transmembrane protein 106A -74706 (+) LOC100130581|uncharacterized LOC100130581 27105 (-)

chr1:147994170..147994360 11.052 PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G -38868 (-) NBPF14|neuroblastoma breakpoint family, member 14 NBPF1|neuroblastoma breakpoint family, member 1 31589 (-)

chr1:148241480..148241613 10.828 PPIAL4D|peptidylprolyl isomerase A (cyclophilin A)-like 4D PPIAL4F|peptidylprolyl isomerase A (cyclophilin A)-like 4F -39011 (-) NBPF15|neuroblastoma breakpoint family, member 15 316681 (+)

chr1:28975108..28975276 10.745 TAF12|TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -5612 (-) GMEB1|glucocorticoid modulatory element binding protein 1 20037 (+)

26:0.691

chr13:114103532..114103717 10.717 ADPRHL1|ADP-ribosylhydrolase like 1 -170 (-) ADPRHL1|ADP-ribosylhydrolase like 1 4214 (-)

-9:0.293, 24:0.292, 58:0.293, -76:0.293, 91:0.293, -110:0.293

-74:0.261, 93:0.261, -108:0.261

chr2:3622714..3622828 10.680 RNASEH1|ribonuclease H1 -16829 (-) 8 (-)

21:0.754

chr1:149514074..149514238 10.639 HIST2H2BF|histone cluster 2, H2bf -114960 (-) PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4C|peptidylprolyl isomerase A (cyclophilin A)-like 4C PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G 38867 (+)

chr8:56987084..56987232 10.381 RPS20|ribosomal protein S20 -72 (-) MOS|v-mos Moloney murine sarcoma viral oncogene homolog 39382 (-)

-23:0.517

chr17:56709001..56709186 10.355 C17orf47|chromosome 17 open reading frame 47 -87386 (-) TEX14|testis expressed 14 60302 (-)

chr17:56736476..56736667 10.334 C17orf47|chromosome 17 open reading frame 47 -114864 (-) TEX14|testis expressed 14 32824 (-)

chr12:38710443..38710582 10.317 ALG10|asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe) -4535039 (+) ALG10B|asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast) 113 (+)

3:0.299, 56:0.328, -76:0.620

43:0.923

chr1:148604852..148605039 10.273 NBPF15|neuroblastoma breakpoint family, member 15 NBPF16|neuroblastoma breakpoint family, member 16 -27529 (+) PPIAL4E|peptidylprolyl isomerase A (cyclophilin A)-like 4E 39065 (+)

chr17:56756866..56757049 10.263 C17orf47|chromosome 17 open reading frame 47 -135250 (-) TEX14|testis expressed 14 12438 (-)

chr18:9841..10032 10.251 None (None) USP14|ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 148594 (+)

chr16:89307471..89307659 10.249 ZNF778|zinc finger protein 778 -23438 (+) ANKRD11|ankyrin repeat domain 11 42509 (-)

-3:0.744, 26:0.744, -33:0.744, 56:0.744, -63:0.744, 86:0.744, -93:0.744, 116:0.744

chr1:11969787..11969943 10.248 NPPB|natriuretic peptide B -50925 (-) KIAA2013|KIAA2013 16608 (-)

chr1:45196644..45196834 10.216 C1orf228|chromosome 1 open reading frame 228 -56346 (+) KIF2C|kinesin family member 2C 8759 (+)

chr17:18965281..18965359 10.159 GRAP|GRB2-related adaptor protein -15034 (-) GRAPL|GRB2-related adaptor protein-like 65461 (+)

-11:0.293

48:0.283

chr8:143751378..143751483 10.152 JRK|jerky homolog (mouse) -29 (-) PSCA|prostate stem cell antigen 10476 (+)

10:0.774, -48:0.896

chr1:149605958..149606137 10.105 PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4C|peptidylprolyl isomerase A (cyclophilin A)-like 4C PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G -53024 (+) FCGR1A|Fc fragment of IgG, high affinity Ia, receptor (CD64) 148225 (+)

chr15:65597073..65597244 10.098 PARP16|poly (ADP-ribose) polymerase family, member 16 -17998 (-) IGDCC3|immunoglobulin superfamily, DCC subclass, member 3 73193 (-)

chr1:146556130..146556321 10.049 NBPF11|neuroblastoma breakpoint family, member 11 NBPF24|neuroblastoma breakpoint family, member 24 -473527 (-) PRKAB2|protein kinase, AMP-activated, beta 2 non-catalytic subunit 87540 (-)

92:0.535

chr3:73160038..73160170 9.990 EBLN2|endogenous Bornavirus-like nucleoprotein 2 -49295 (+) PDZRN3|PDZ domain containing ring finger 3 513934 (-)

chr1:148241615..148241804 9.986 PPIAL4D|peptidylprolyl isomerase A (cyclophilin A)-like 4D PPIAL4F|peptidylprolyl isomerase A (cyclophilin A)-like 4F -39174 (-) NBPF15|neuroblastoma breakpoint family, member 15 316518 (+)

chr1:9991..10182 9.961 None (None) WASH2P|WAS protein family homolog 2 pseudogene WASH3P|WAS protein family homolog 3 pseudogene WASH7P|WAS protein family homolog 7 pseudogene 19319 (-)

chr1:38455703..38455849 9.950 SF3A3|splicing factor 3a, subunit 3, 60kDa -78 (-) FHL3|four and a half LIM domains 3 15457 (-)

-15:0.896, -91:0.643

61:0.994, 114:0.643

64:0.679, -85:0.338

chr1:1310586..1310706 9.895 AURKAIP1|aurora kinase A interacting protein 1 -73 (-) AURKAIP1|aurora kinase A interacting protein 1 217 (-)

-64:0.912, 68:0.358

chr2:224822085..224822198 9.860 WDFY1|WD repeat and FYVE domain containing 1 -12076 (-) MRPL44|mitochondrial ribosomal protein L44 12 (+)

chr7:141437993..141438136 9.859 WEE2|WEE1 homolog 2 (S. pombe) -29912 (+) SSBP1|single-stranded DNA binding protein 1 200 (+)

102:0.896

57:0.276

chr4:106629830..106629947 9.712 INTS12|integrator complex subunit 12 -47 (-) GSTCD|glutathione S-transferase, C-terminal domain containing 85 (+)

45:0.261, 67:0.233

chr1:143647004..143647126 9.704 -179440 (-) FLJ39739|uncharacterized FLJ39739 LOC100286793|uncharacterized LOC100286793 97340 (-)

chr21:26950692..26950883 9.676 MIR155HG|MIR155 host gene (non-protein coding) -16315 (+) MRPL39|mitochondrial ribosomal protein L39 29028 (-)

-112:0.911

chr1:147834492..147834613 9.640 NBPF24|neuroblastoma breakpoint family, member 24 -209952 (-) FLJ39739|uncharacterized FLJ39739 97376 (-)

chr14:35016190..35016381 9.516 EAPP|E2F-associated phosphoprotein -7400 (-) SNX6|sorting nexin 6 83070 (-)

99:0.379, -106:0.336

chr14:35025132..35025323 9.497 EAPP|E2F-associated phosphoprotein -16342 (-) SNX6|sorting nexin 6 74128 (-)

-95:0.379, 110:0.336

chr1:148766903..148767094 9.493 NBPF15|neuroblastoma breakpoint family, member 15 NBPF16|neuroblastoma breakpoint family, member 16 NBPF8|neuroblastoma breakpoint family, member 8 -27497 (+) PPIAL4D|peptidylprolyl isomerase A (cyclophilin A)-like 4D PPIAL4F|peptidylprolyl isomerase A (cyclophilin A)-like 4F 39016 (+)

chr2:122288448..122288638 9.447 CLASP1|cytoplasmic linker associated protein 1 -40624 (-) CLASP1|cytoplasmic linker associated protein 1 118479 (-)

-117:0.779

42:0.257

chr1:45285491..45285681 9.406 BTBD19|BTB (POZ) domain containing 19 -11376 (+) PTCH2|patched 2 23051 (-)

-22:0.318, 94:0.541

chr1:9798..9919 9.406 None (None) WASH2P|WAS protein family homolog 2 pseudogene WASH3P|WAS protein family homolog 3 pseudogene WASH7P|WAS protein family homolog 7 pseudogene 19547 (-)

chr1:147806722..147806888 9.396 NBPF24|neuroblastoma breakpoint family, member 24 -182205 (-) FLJ39739|uncharacterized FLJ39739 125123 (-)

chr1:145382834..145382997 9.385 NBPF10|neuroblastoma breakpoint family, member 10 NBPF8|neuroblastoma breakpoint family, member 8 -89614 (+) HFE2|hemochromatosis type 2 (juvenile) 30348 (+)

chr17:41393253..41393444 9.360 TMEM106A|transmembrane protein 106A -29469 (+) LOC100130581|uncharacterized LOC100130581 72342 (-)

chr18:10082..10273 9.360 None (None) USP14|ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 148353 (+)

chr1_gl000192_random:544946..545096 9.352 None None (None) None None (None)

chr2:242041713..242041847 9.338 MTERFD2|MTERF domain containing 2 -54 (-) PASK|PAS domain containing serine/threonine kinase 47091 (-)

-27:0.896, -56:0.644, 109:0.289

chr1:144534125..144534305 9.335 FAM91A2|family with sequence similarity 91, member A2 -12986 (-) NBPF10|neuroblastoma breakpoint family, member 10 59483 (+)

chr17:30771379..30771510 9.312 ZNF207|zinc finger protein 207 -94199 (+) PSMD11|proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 45 (+)

53:0.354

-18:0.954

-109:0.886

chr6:89773263..89773342 9.301 RNGTT|RNA guanylyltransferase and 5'-phosphatase -99955 (-) PNRC1|proline-rich nuclear receptor coactivator 1 17135 (+)

chr15:49913173..49913297 9.243 C15orf33|chromosome 15 open reading frame 33 -152 (-) DTWD1|DTW domain containing 1 14 (+)

-32:0.390

chr15:64679902..64680055 9.242 KIAA0101|KIAA0101 -6343 (-) TRIP4|thyroid hormone receptor interactor 4 58 (+)

-83:0.429, -102:0.264

chr1:205091360..205091478 9.235 RBBP5|retinoblastoma binding protein 5 -272 (-) DSTYK|dual serine/threonine and tyrosine protein kinase 89254 (-)

15:0.203

chr1:40723777..40723914 9.181 ZMPSTE24|zinc metallopeptidase (STE24 homolog, S. cerevisiae) -69 (+) ZMPSTE24|zinc metallopeptidase (STE24 homolog, S. cerevisiae) 1 (+)

chr2:74682029..74682197 9.176 RTKN|rhotekin -13048 (-) INO80B|INO80 complex subunit B 91 (+)

28:0.825

chr17:19091579..19091770 9.151 GRAPL|GRB2-related adaptor protein-like -60893 (+) EPN2|epsin 2 49034 (+)

12:0.240

chr17:41445248..41445439 9.141 TMEM106A|transmembrane protein 106A -81464 (+) LOC100130581|uncharacterized LOC100130581 20347 (-)

chr1:144311193..144311351 9.136 FAM72D|family with sequence similarity 72, member D -398142 (-) PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4C|peptidylprolyl isomerase A (cyclophilin A)-like 4C PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G 52952 (-)

chr12:120729320..120729510 9.129 PXN|paxillin -25825 (-) SIRT4|sirtuin 4 10727 (+)

chr12:120730885..120731066 9.116 PXN|paxillin -27385 (-) SIRT4|sirtuin 4 9167 (+)

chr1:144491423..144491580 9.107 PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4C|peptidylprolyl isomerase A (cyclophilin A)-like 4C PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G -127277 (-) LOC728855|uncharacterized LOC728855 29430 (-)

chr12:34175297..34175429 9.103 ALG10|asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe) -148 (+) ALG10|asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe) 23 (+)

45:0.328, -88:0.560

32:0.923

chr1:205180810..205180927 9.054 DSTYK|dual serine/threonine and tyrosine protein kinase -149 (-) TMCC2|transmembrane and coiled-coil domain family 2 16215 (+)

49:0.990

chr1:999654..999845 9.044 LOC100288175|uncharacterized LOC100288175 -4637 (+) RNF223|ring finger protein 223 9937 (-)

-91:0.602

-120:0.240

chr19:59031191..59031381 9.012 ZBTB45|zinc finger and BTB domain containing 45 -98 (-) TRIM28|tripartite motif containing 28 24546 (+)

-31:0.588, 90:0.647, -106:0.882

chr21:26950267..26950458 9.011 MIR155HG|MIR155 host gene (non-protein coding) -15890 (+) MRPL39|mitochondrial ribosomal protein L39 29453 (-)

-40:0.310

chr11:64863542..64863672 9.001 LOC100130348|uncharacterized LOC100130348 LOC399904|uncharacterized LOC399904 -7048 (-) C11orf2|chromosome 11 open reading frame 2 38 (+)

55:0.880, -92:0.313

chrX:73164042..73164173 8.972 CHIC1|cysteine-rich hydrophobic domain 1 -380881 (+) JPX|JPX transcript, XIST activator (non-protein coding) 62 (+)

-46:0.389, -63:0.436, -80:0.434, -97:0.434

chr21:26951019..26951210 8.958 MIR155HG|MIR155 host gene (non-protein coding) -16642 (+) MRPL39|mitochondrial ribosomal protein L39 28701 (-)

chr22:23101293..23101484 8.953 IGLJ3|immunoglobulin lambda joining 3 -38257 (+) 33718 (+)

chr14:61201380..61201514 8.874 SIX4|SIX homeobox 4 -10390 (-) MNAT1|menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) 68 (+)

chr2:88315874..88316062 8.865 RGPD1|RANBP2-like and GRIP domain containing 1 -30660 (-) KRCC1|lysine-rich coiled-coil 1 39291 (-)

chr13:53191536..53191662 8.805 CKAP2|cytoskeleton associated protein 2 -156306 (+) HNRNPA1L2|heterogeneous nuclear ribonucleoprotein A1-like 2 38 (+)

18:0.202

chr16:2732411..2732535 8.799 ERVK13-1|endogenous retrovirus group K13, member 1 -9068 (-) KCTD5|potassium channel tetramerisation domain containing 5 26 (+)

40:0.823, -52:0.430, -57:0.224, -90:0.794

chr6:157744522..157744658 8.790 TMEM242|transmembrane protein 242 -6 (-) TMEM242|transmembrane protein 242 627 (-)

30:0.445

chr14:70826418..70826552 8.783 COX16|COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -65 (-) SYNJ2BP-COX16|SYNJ2BP-COX16 readthrough SYNJ2BP|synaptojanin 2 binding protein 57271 (-)

-75:0.506

-74:0.638

chr1:11968465..11968655 8.762 NPPB|natriuretic peptide B -49620 (-) KIAA2013|KIAA2013 17913 (-)

chr10:43278119..43278252 8.755 BMS1|BMS1 homolog, ribosome assembly protein (yeast) -232 (+) BMS1|BMS1 homolog, ribosome assembly protein (yeast) 65 (+)

49:0.503

chr5:74062947..74063072 8.735 GFM2|G elongation factor, mitochondrial 2 -46 (-) NSA2|NSA2 ribosome biogenesis homolog (S. cerevisiae) 78 (+)

-18:0.331, -57:0.896

chr2:24299205..24299332 8.730 SF3B14|splicing factor 3B, 14 kDa subunit -97 (-) SF3B14|splicing factor 3B, 14 kDa subunit 53 (-)

53:0.476, -55:0.660, 83:0.882

chr11:66189209..66189341 8.720 NPAS4|neuronal PAS domain protein 4 -714 (+) MRPL11|mitochondrial ribosomal protein L11 17011 (-)

chr1:163291561..163291692 8.716 -65 (-) NUF2|NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) 150 (+)

-48:0.885, -115:0.496

chr5:68855907..68856047 8.713 OCLN|occludin -55940 (+) GTF2H2B|general transcription factor IIH, polypeptide 2B (pseudogene) GTF2H2C|general transcription factor IIH, polypeptide 2C GTF2H2D|general transcription factor IIH, polypeptide 2D 64 (+)

19:0.744, 64:0.371

-39:0.272

chr15:96289163..96289245 8.701 LOC400456|uncharacterized LOC400456 -418885 (-) NR2F2|nuclear receptor subfamily 2, group F, member 2 579957 (+)

chr6:131949358..131949506 8.695 MED23|mediator complex subunit 23 -145 (-) ENPP3|ectonucleotide pyrophosphatase/phosphodiesterase 3 9050 (+)

-118:0.508

115:0.947

-71:0.550

chr4:4543759..4543877 8.694 STX18|syntaxin 18 -57 (-) LOC100507266|uncharacterized LOC100507266 66 (+)

chr20:57226180..57226314 8.683 APCDD1L|adenomatosis polyposis coli down-regulated 1-like -136349 (-) STX16-NPEPL1|STX16-NPEPL1 readthrough (non-protein coding) STX16|syntaxin 16 141 (+)

21:0.663

-98:0.529

-91:0.273

chr22:19419942..19420080 8.682 MRPL40|mitochondrial ribosomal protein L40 -629 (+) MRPL40|mitochondrial ribosomal protein L40 36 (+)

50:0.774

9:0.589

chr1:148604631..148604821 8.651 NBPF15|neuroblastoma breakpoint family, member 15 NBPF16|neuroblastoma breakpoint family, member 16 -27310 (+) PPIAL4E|peptidylprolyl isomerase A (cyclophilin A)-like 4E 39284 (+)

chr3:53381602..53381745 8.644 DCP1A|DCP1 decapping enzyme homolog A (S. cerevisiae) -80 (-) CACNA1D|calcium channel, voltage-dependent, L type, alpha 1D subunit 146986 (+)

-28:0.555

chr1:45196424..45196615 8.634 C1orf228|chromosome 1 open reading frame 228 -56126 (+) KIF2C|kinesin family member 2C 8979 (+)

chr1:147994416..147994606 8.626 PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G -39114 (-) NBPF14|neuroblastoma breakpoint family, member 14 NBPF1|neuroblastoma breakpoint family, member 1 31343 (-)

chr20:40322124..40322240 8.622 CHD6|chromodomain helicase DNA binding protein 6 -75121 (-) PTPRT|protein tyrosine phosphatase, receptor type, T 1496328 (-)

50:0.496

chr1:148766672..148766862 8.602 NBPF15|neuroblastoma breakpoint family, member 15 NBPF16|neuroblastoma breakpoint family, member 16 NBPF8|neuroblastoma breakpoint family, member 8 -27266 (+) PPIAL4D|peptidylprolyl isomerase A (cyclophilin A)-like 4D PPIAL4F|peptidylprolyl isomerase A (cyclophilin A)-like 4F 39247 (+)

chr11:68671280..68671406 8.601 IGHMBP2|immunoglobulin mu binding protein 2 -8 (+) IGHMBP2|immunoglobulin mu binding protein 2 22 (+)

-45:0.505

chr13:31191951..31192064 8.594 USPL1|ubiquitin specific peptidase like 1 -44 (+) ALOX5AP|arachidonate 5-lipoxygenase-activating protein 95607 (+)

11:0.300, 44:0.606, -51:0.912

chr13:46948594..46948687 8.582 LCP1|lymphocyte cytosolic protein 1 (L-plastin) -192248 (-) KIAA0226L|KIAA0226-like 12705 (-)

chr17:61678149..61678279 8.582 DCAF7|DDB1 and CUL4 associated factor 7 -50202 (+) TACO1|translational activator of mitochondrially encoded cytochrome c oxidase I 18 (+)

13:0.518

chr17:18966920..18967111 8.539 GRAP|GRB2-related adaptor protein -16729 (-) GRAPL|GRB2-related adaptor protein-like 63766 (+)

75:0.240

chr5:70363504..70363634 8.527 GTF2H2B|general transcription factor IIH, polypeptide 2B (pseudogene) GTF2H2C|general transcription factor IIH, polypeptide 2C GTF2H2|general transcription factor IIH, polypeptide 2, 44kDa -115 (-) BDP1|B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 387907 (+)

-14:0.744, -59:0.371

44:0.272

chr12:7052974..7053151 8.526 -7606 (+) C12orf57|chromosome 12 open reading frame 57 135 (+)

100:0.797

chr22:23241979..23242170 8.500 IGLC1|immunoglobulin lambda constant 1 (Mcg marker) IGLL5|immunoglobulin lambda-like polypeptide 5 -11991 (+) GNAZ|guanine nucleotide binding protein (G protein), alpha z polypeptide 170442 (+)

chr1:78470069..78470212 8.497 DNAJB4|DnaJ (Hsp40) homolog, subfamily B, member 4 -25168 (+) DNAJB4|DnaJ (Hsp40) homolog, subfamily B, member 4 474 (+)

chr1:210547281..210547471 8.493 HHAT|hedgehog acyltransferase -44735 (+) KCNH1|potassium voltage-gated channel, subfamily H (eag-related), member 1 760009 (-)

chr1:17231638..17231829 8.483 CROCCP2|ciliary rootlet coiled-coil, rootletin pseudogene 2 -260556 (-) CROCC|ciliary rootlet coiled-coil, rootletin 16701 (+)

-51:0.555

chr5:69711064..69711195 8.465 SMA4|glucuronidase, beta pseudogene -14210 (+) SMA4|glucuronidase, beta pseudogene 170901 (-)

14:0.744, 59:0.371

-44:0.272

chrUn_gl000219:99792..99983 8.465 None None (None) None None (None)

chr1:149513847..149514030 8.463 HIST2H2BF|histone cluster 2, H2bf -114742 (-) PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4C|peptidylprolyl isomerase A (cyclophilin A)-like 4C PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G 39085 (+)

chr17:8076474..8076664 8.458 VAMP2|vesicle-associated membrane protein 2 (synaptobrevin 2) -10277 (-) TMEM107|transmembrane protein 107 3091 (-)

chr9:108006607..108006740 8.438 ABCA1|ATP-binding cassette, sub-family A (ABC1), member 1 -316144 (-) SLC44A1|solute carrier family 44, member 1 240 (+)

22:0.209, -120:0.438

chr1:45187142..45187333 8.434 C1orf228|chromosome 1 open reading frame 228 -46844 (+) KIF2C|kinesin family member 2C 18261 (+)

chr1:179851835..179851955 8.426 TOR1AIP1|torsin A interacting protein 1 -80 (+) TOR1AIP1|torsin A interacting protein 1 21 (+)

12:0.338, 35:0.730, 104:0.303

107:0.362

34:0.992

chr14:24658116..24658229 8.422 IPO4|importin 4 -106 (-) TM9SF1|transmembrane 9 superfamily member 1 6474 (-)

-15:0.546, -101:0.775

chr6:100016520..100016674 8.410 CCNC|cyclin C -140 (-) CCNC|cyclin C 6 (-)

27:0.351

chr9:37800681..37800811 8.410 EXOSC3|exosome component 3 -15677 (-) DCAF10|DDB1 and CUL4 associated factor 10 38 (+)

40:0.896

chr16:89160174..89160328 8.402 ACSF3|acyl-CoA synthetase family member 3 -14 (+) ACSF3|acyl-CoA synthetase family member 3 56 (+)

21:0.522, 104:0.293

chr15:35261934..35262073 8.389 AQR|aquarius homolog (mouse) -76 (-) ZNF770|zinc finger protein 770 18451 (-)

20:0.809

89:0.239

chr17:29233229..29233370 8.382 C17orf42|chromosome 17 open reading frame 42 -48 (-) ADAP2|ArfGAP with dual PH domains 2 15533 (+)

-40:0.736

chr15:65903442..65903573 8.374 PTPLAD1|protein tyrosine phosphatase-like A domain containing 1 -80584 (+) C15orf44|chromosome 15 open reading frame 44 9 (-)

7:0.334

chr3:194393170..194393310 8.367 LSG1|large subunit GTPase 1 homolog (S. cerevisiae) -35 (-) FAM43A|family with sequence similarity 43, member A 13383 (+)

59:0.324

chr20:2451394..2451546 8.365 SNRPB|small nuclear ribonucleoprotein polypeptides B and B1 -38 (-) SNRPB|small nuclear ribonucleoprotein polypeptides B and B1 3 (-)

2:0.826, 29:0.299, -40:0.756, 120:0.367

chr1:212965126..212965263 8.363 NSL1|NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) -73 (-) TATDN3|TatD DNase domain containing 3 24 (+)

-60:0.998

chr22:22337178..22337298 8.359 TOP3B|topoisomerase (DNA) III beta -52 (-) 48127 (+)

-44:0.510

chr2:197664394..197664532 8.356 GTF3C3|general transcription factor IIIC, polypeptide 3, 102kDa -50 (-) C2orf66|chromosome 2 open reading frame 66 10474 (-)

-77:0.688, -96:0.279

14:0.442

chr10:14227689..14227879 8.344 FRMD4A|FERM domain containing 4A -177292 (-) FRMD4A|FERM domain containing 4A 145066 (-)

-46:0.234

chr3:185216746..185216862 8.339 TMEM41A|transmembrane protein 41A -105 (-) LIPH|lipase, member H 53524 (-)

chr3:131221770..131221915 8.329 MRPL3|mitochondrial ribosomal protein L3 -88 (-) CPNE4|copine IV 531998 (-)

1:0.912, 47:0.339

chr21:26948608..26948799 8.327 MIR155HG|MIR155 host gene (non-protein coding) -14231 (+) MRPL39|mitochondrial ribosomal protein L39 31112 (-)

62:0.214

chr5:133968507..133968614 8.320 SAR1B|SAR1 homolog B (S. cerevisiae) -63 (-) SEC24A|SEC24 family, member A (S. cerevisiae) 15871 (+)

-36:0.475

31:0.219

chr10:14227466..14227657 8.306 FRMD4A|FERM domain containing 4A -177069 (-) FRMD4A|FERM domain containing 4A 145289 (-)

78:0.319

chr3:149470274..149470412 8.304 COMMD2|COMM domain containing 2 -73 (-) ANKUB1|ankyrin repeat and ubiquitin domain containing 1 40266 (-)

-58:0.896

chr5:40835355..40835488 8.300 RPL37|ribosomal protein L37 -66 (-) CARD6|caspase recruitment domain family, member 6 6021 (+)

-45:0.885, 59:0.239, -63:0.363, -87:0.751, -101:0.687

chr15:65588630..65588821 8.291 PARP16|poly (ADP-ribose) polymerase family, member 16 -9565 (-) IGDCC3|immunoglobulin superfamily, DCC subclass, member 3 81626 (-)

chr4:26585560..26585695 8.289 CCKAR|cholecystokinin A receptor -93642 (-) TBC1D19|TBC1 domain family, member 19 53 (+)

48:0.408

chr1:44679028..44679137 8.287 KLF17|Kruppel-like factor 17 -94533 (+) DMAP1|DNA methyltransferase 1 associated protein 1 61 (+)

12:0.912, 52:0.809

104:0.919

chr1:45285262..45285452 8.279 BTBD19|BTB (POZ) domain containing 19 -11147 (+) PTCH2|patched 2 23280 (-)

chr4:9927..10118 8.264 None (None) ZNF595|zinc finger protein 595 ZNF718|zinc finger protein 718 43202 (+)

chrUn_gl000219:100027..100173 8.264 None None (None) None None (None)

25:0.247, -101:0.329, 102:0.338

chr11:57508760..57508899 8.261 TMX2-CTNND1|TMX2-CTNND1 readthrough (non-protein coding) TMX2|thioredoxin-related transmembrane protein 2 -28759 (+) C11orf31|chromosome 11 open reading frame 31 23 (+)

-57:0.482

chr17:49230801..49230928 8.246 SPAG9|sperm associated antigen 9 -32709 (-) NME1-NME2|NME1-NME2 readthrough NME1|non-metastatic cells 1, protein (NM23A) expressed in 47 (+)

3:0.553, -48:0.810, -73:0.275

chr7:129691167..129691294 8.245 ZC3HC1|zinc finger, C3HC-type containing 1 -9 (-) KLHDC10|kelch domain containing 10 19130 (+)

27:0.286

chr14:23039192..23039335 8.233 -49914 (+) DAD1|defender against cell death 1 18823 (-)

19:0.332

chr17:17991120..17991262 8.224 C17orf39|chromosome 17 open reading frame 39 -48384 (+) DRG2|developmentally regulated GTP binding protein 2 77 (+)

58:0.572, 95:0.220

chr13:53226925..53227066 8.219 SUGT1|SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) -53 (+) LECT1|leukocyte cell derived chemotaxin 1 86869 (-)

80:0.494

-118:0.387

70:0.232

chr1:28975334..28975525 8.212 TAF12|TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -5849 (-) GMEB1|glucocorticoid modulatory element binding protein 1 19800 (+)

56:0.267

chr11:65769628..65769757 8.202 EIF1AD|eukaryotic translation initiation factor 1A domain containing -62 (-) BANF1|barrier to autointegration factor 1 127 (+)

28:0.270, 52:0.296, -62:0.798

chr13:52768540..52768672 8.202 THSD1P1|thrombospondin, type I, domain containing 1 pseudogene 1 -47 (-) THSD1|thrombospondin, type I, domain containing 1 211672 (-)

-9:0.588

chr15:75660926..75661049 8.187 MAN2C1|mannosidase, alpha, class 2C, member 1 -30 (-) SIN3A|SIN3 transcription regulator homolog A (yeast) 82915 (-)

0:0.294

21:0.315

85:0.818

chr17:57287297..57287406 8.180 PRR11|proline rich 11 -54231 (+) SMG8|smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) 46 (+)

-30:0.493, 35:0.364

-31:0.463

chr17:56756601..56756792 8.170 C17orf47|chromosome 17 open reading frame 47 -134989 (-) TEX14|testis expressed 14 12699 (-)

chr11:65274632..65274822 8.163 -3217 (+) SCYL1|SCY1-like 1 (S. cerevisiae) 17810 (+)

chr5:102455840..102455980 8.158 GIN1|gypsy retrotransposon integrase 1 -97 (-) PPIP5K2|diphosphoinositol pentakisphosphate kinase 2 71 (+)

18:0.500, -76:0.768, -104:0.380

-52:0.216

chr8:33371036..33371224 8.158 TTI2|TELO2 interacting protein 2 -503 (-) RNF122|ring finger protein 122 53533 (-)

chr19:50879538..50879664 8.157 NAPSA|napsin A aspartic peptidase -10698 (-) NR1H2|nuclear receptor subfamily 1, group H, member 2 126 (+)

16:0.836, 34:0.301, -36:0.368, 75:0.836, 107:0.438

chr10:95462357..95462472 8.130 FRA10AC1|fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 -79 (-) LGI1|leucine-rich, glioma inactivated 1 55232 (+)

48:0.215, -66:0.912

chr1:999888..999971 8.121 LOC100288175|uncharacterized LOC100288175 -4817 (+) RNF223|ring finger protein 223 9757 (-)

-7:0.622

chr15:41694669..41694792 8.119 NDUFAF1|NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 -68 (-) RTF1|Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 14630 (+)

19:0.351, 42:0.270

chr13:113862979..113863108 8.112 PCID2|PCI domain containing 2 -57 (-) CUL4A|cullin 4A 58 (+)

-31:0.896

chr21:26979781..26979925 8.102 MRPL39|mitochondrial ribosomal protein L39 -38 (-) JAM2|junctional adhesion molecule 2 31800 (+)

-13:0.288

62:0.582

chr1:227922986..227923112 8.097 JMJD4|jumonji domain containing 4 -78 (-) JMJD4|jumonji domain containing 4 50 (-)

-24:0.295, -36:0.715, -112:0.255

chr5:149780345..149780535 8.095 TCOF1|Treacher Collins-Franceschetti syndrome 1 -43116 (+) CD74|CD74 molecule, major histocompatibility complex, class II invariant chain 11863 (-)

chr20:31989334..31989427 8.093 CDK5RAP1|CDK5 regulatory subunit associated protein 1 -41 (-) SNTA1|syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 42181 (-)

-7:0.495, -45:0.311

chr4:25314309..25314440 8.090 PI4K2B|phosphatidylinositol 4-kinase type 2 beta -78656 (+) ZCCHC4|zinc finger, CCHC domain containing 4 73 (+)

-31:0.378, 56:0.228

chr19:11039373..11039510 8.078 YIPF2|Yip1 domain family, member 2 -202 (-) C19orf52|chromosome 19 open reading frame 52 16 (+)

-40:0.912

chrX:12993298..12993488 8.069 TMSB4X|thymosin beta 4, X-linked -153 (+) TMSB4X|thymosin beta 4, X-linked 950 (+)

chr1:1310758..1310929 8.065 AURKAIP1|aurora kinase A interacting protein 1 -270 (-) AURKAIP1|aurora kinase A interacting protein 1 20 (-)

7:0.342, 46:0.501, 68:0.304, 89:0.546, 112:0.535

-42:0.224

chr1:206785771..206785884 8.064 EIF2D|eukaryotic translation initiation factor 2D -72 (-) EIF2D|eukaryotic translation initiation factor 2D 56 (-)

-62:0.503

chr2:55496339..55496466 8.063 MTIF2|mitochondrial translational initiation factor 2 -37 (-) CCDC88A|coiled-coil domain containing 88A 63384 (-)

9:0.648, -40:0.422

chr14:106319928..106320119 8.061 IGHM|immunoglobulin heavy constant mu -82319 (-) 1658 (-)

chr16:2653279..2653422 8.045 PDPK1|3-phosphoinositide dependent protein kinase-1 -65243 (+) LOC652276|potassium channel tetramerisation domain containing 5 pseudogene 67 (+)

-3:0.551, -41:0.782, 85:0.687

-51:0.419

chr16:740391..740500 8.043 WDR24|WD repeat domain 24 -43 (-) FBXL16|F-box and leucine-rich repeat protein 16 15370 (-)

9:0.770, -22:0.896, 46:0.319, -51:0.606

chr17:42092311..42092456 8.037 TMEM101|transmembrane protein 101 -17 (-) LSM12|LSM12 homolog (S. cerevisiae) 51583 (-)

9:0.628, 41:0.308

chr1:150209425..150209536 8.034 ANP32E|acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -988 (-) CA14|carbonic anhydrase XIV 20753 (+)

-53:0.390

chr4:164415676..164415830 8.034 C4orf43|chromosome 4 open reading frame 43 -35 (+) C4orf43|chromosome 4 open reading frame 43 63 (+)

63:0.218, -65:0.221

chr4:78783795..78783986 8.017 CNOT6L|CCR4-NOT transcription complex, subunit 6-like -43346 (-) MRPL1|mitochondrial ribosomal protein L1 24 (+)

-96:0.215

-3:0.313

chr3:155572258..155572388 8.014 SLC33A1|solute carrier family 33 (acetyl-CoA transporter), member 1 -117 (-) GMPS|guanine monphosphate synthetase 15978 (+)

-80:0.768, -98:0.792

chr19:1383782..1383904 7.989 MUM1|melanoma associated antigen (mutated) 1 -28842 (+) NDUFS7|NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 43 (+)

-19:0.219

chr4:83955984..83956143 7.985 LIN54|lin-54 homolog (C. elegans) -22035 (-) COPS4|COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) 261 (+)

chr8:95731987..95732098 7.958 ESRP1|epithelial splicing regulatory protein 1 -78598 (+) DPY19L4|dpy-19-like 4 (C. elegans) 98 (+)

-57:0.300, 66:0.770

chr20:1099108..1099252 7.952 PSMF1|proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -5220 (+) PSMF1|proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 173 (+)

-51:0.606, 62:0.797

chr9:114393400..114393523 7.951 PTGR1|prostaglandin reductase 1 -31344 (-) DNAJC25-GNG10|DNAJC25-GNG10 readthrough DNAJC25|DnaJ (Hsp40) homolog, subfamily C , member 25 154 (+)

32:0.684, 83:0.291

-3:0.865

chr9:140473318..140473484 7.944 WDR85|WD repeat domain 85 -29 (-) ZMYND19|zinc finger, MYND-type containing 19 11531 (-)

-19:0.293

58:0.541

chr1:150459668..150459813 7.942 RPRD2|regulation of nuclear pre-mRNA domain containing 2 -122518 (+) TARS2|threonyl-tRNA synthetase 2, mitochondrial (putative) 152 (+)

-16:0.457, 45:0.249

52:0.215

15:0.301

chr1:143673162..143673283 7.937 -205597 (-) FLJ39739|uncharacterized FLJ39739 LOC100286793|uncharacterized LOC100286793 71183 (-)

chr13:41345297..41345429 7.930 MRPS31|mitochondrial ribosomal protein S31 -31 (-) SLC25A15|solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 18226 (+)

-7:0.705

chr21:46359832..46359937 7.925 C21orf67|chromosome 21 open reading frame 67 -121 (-) FAM207A|family with sequence similarity 207, member A 41 (+)

-23:0.798, -33:0.774, 47:0.627

Examples of peaks fitted within regions

Complementary Motifs Enriched In Peaks:

Motif Name

Sequence Logo

Motif Ensemble Enrichment (Motif Ensemble log-Likelihood Ratio)

Enrichment (log-Likelihood Ratio)

Precision and Recall

Prediction - Observation Correlation

Enrichment at Binding Sites

Number of Positively Predicted Peaks

HCMC.ELF1_f1.wm 1.76 (281.449) 1.76 (281.449) 0.3921 0.12 1.4332 9381/19318
HCMC.IRF8_si.wm 2.065 (361.044) 1.213 (96.319) 0.2398 -0.0063 1.3902 2213/19318
ZNF143.p2 2.296 (413.814) 1.101 (47.801) 0.1787 0.0528 1.8131 870/19318
denovo_WM_17 2.574 (470.775) 1.079 (38.009) 0.1628 0.0261 1.1385 696/19318
HCMC.CTCF_f2.wm 2.756 (504.833) 1.136 (63.708) 0.2121 0.0079 1.6575 3715/19318
denovo_WM_21 2.888 (528.075) 1.087 (41.401) 0.1797 0.0193 0.8191 871/19318
HCMC.SPI1_si.wm 3.011 (549.002) 1.253 (112.137) 0.2631 -0.0111 1.4773 1829/19318
JASPAR.Myf.wm 3.122 (566.951) 1.067 (32.387) 0.1827 -0.0098 1.2066 3830/19318
HCMC.FOXM1_f1.wm 3.207 (580.41) 1.034 (16.755) 0.1466 -0.0201 0.8306 69/19318

Contribution and Correlation Plots

Top Motifs Enriched In Peaks:

Motif Name

Sequence Logo

Enrichment (log-Likelihood Ratio)

Precision and Recall

Prediction - Observation Correlation

Enrichment at Binding Sites

Number of Positively Predicted Peaks

HCMC.ELF1_f1.wm 1.76 (281.449) 0.3921 0.12 1.4332 9381/19318
HCMC.ETV4_f1.wm 1.729 (272.624) 0.4179 0.0645 1.1907 18436/19318
HCMC.GABP1+GABP2_f1.wm 1.679 (258.053) 0.3703 0.1238 1.3765 10867/19318
JASPAR.SPI1.wm 1.638 (245.834) 0.3048 0.0013 1.1925 10904/19318
denovo_WM_5 1.617 (239.477) 0.3593 0.1644 1.6543 5806/19318
HCMC.ELK1_f1.wm 1.616 (239.007) 0.3720 0.1515 1.4135 10885/19318
HCMC.ETS1_si.wm 1.613 (238.177) 0.3673 0.0887 1.3254 10917/19318
HCMC.GABPA_f1.wm 1.611 (237.334) 0.3476 0.1343 1.8067 3376/19318
denovo_WM_23 1.601 (234.32) 0.3532 0.1293 1.5143 6335/19318
HCMC.ETS2_f1.wm 1.595 (232.365) 0.3815 0.0775 1.1818 18157/19318

Downloads

BCLAF Replicate 1

BCLAF Replicate 2

BG Replicate 1

BG Replicate 2