CRUNCH Results

QC summary table

QC statistics for this dataset

Comparison with ENCODE datasets

Mapping

Fraction of mapped reads for the IP samples:
0.817
65th percentile
Fraction of mapped reads for the background samples:
0.890
78th percentile

ChIP enrichment signal

Noise level ChIP signal:
0.113
`
11th percentile
Error in fit of enrichment distribution:
0.523
46th percentile

Peak statistics

Number of peaks:
1464
14th percentile
Fraction of reads mapped to peaks:
0.002
8th percentile

Motif enrichment statistics

Enrichment of top motif:
24.11
78th percentile
Enrichment of complimentary motif set:
24.11
76th percentile

Quality Control, Mapping, Fragment Size Estimation:

IRF3 Replicate 1

fragment size plot

IRF3 Replicate 2

fragment size plot

BG Replicate 1

fragment size plot

BG Replicate 2

fragment size plot

Peak Calling:

zvalue histogram reverse cumulative of zvalues

Top peaks:


Coordinates Z-score Nearest Genes on the Left Offset of Nearest TSS on the Left (Strand) Nearest Genes on the Right Offset of Nearest TSS on the Right (Strand) denovo_WM_21
chr21:47604436..47604569 22.805 C21orf56|chromosome 21 open reading frame 56 -127 (-) LSS|lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 44003 (-)

chr11:63953450..63953592 20.703 MACROD1|MACRO domain containing 1 -19966 (-) STIP1|stress-induced-phosphoprotein 1 84 (+)

1:0.910, 41:0.374

chr17:26368506..26368679 19.786 C17orf108|chromosome 17 open reading frame 108 -148201 (-) NLK|nemo-like kinase 1061 (+)

-28:0.900, -70:0.406

chr11:59383371..59383555 19.133 OSBP|oxysterol binding protein -253 (-) OSBP|oxysterol binding protein 153 (-)

-16:0.238, -36:0.947, 79:0.922

chr7:100184107..100184256 18.845 FBXO24|F-box protein 24 -179 (+) FBXO24|F-box protein 24 3042 (+)

2:0.695, -38:0.253

chr17:45973315..45973481 18.830 -248 (-) SP2|Sp2 transcription factor 182 (+)

-28:0.657

chr14:58765022..58765167 18.684 FLJ31306|uncharacterized LOC379025 -261 (-) ARID4A|AT rich interactive domain 4A (RBP1-like) 147 (+)

5:0.717, 73:0.708

chr17:17875917..17876098 18.440 TOM1L2|target of myb1-like 2 (chicken) -266 (-) LRRC48|leucine rich repeat containing 48 193 (+)

chr19:6372587..6372729 18.282 ALKBH7|alkB, alkylation repair homolog 7 (E. coli) -215 (+) ALKBH7|alkB, alkylation repair homolog 7 (E. coli) 96 (+)

chr12:53773609..53773794 17.497 SP7|Sp7 transcription factor -43698 (-) SP1|Sp1 transcription factor 289 (+)

45:0.635, -89:0.411

chr19:14117230..14117401 17.426 RFX1|regulatory factor X, 1 (influences HLA class II expression) -186 (-) RLN3|relaxin 3 21672 (+)

chr11:63953199..63953372 17.293 MACROD1|MACRO domain containing 1 -19730 (-) STIP1|stress-induced-phosphoprotein 1 320 (+)

-54:0.947, 67:0.792

chr9:130829691..130829850 17.267 NAIF1|nuclear apoptosis inducing factor 1 -172 (-) SLC25A25|solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 713 (+)

chr16:30621709..30621839 17.194 ZNF689|zinc finger protein 689 -118 (-) PRR14|proline rich 14 40326 (+)

-10:0.266, 20:0.346

chr17:61627591..61627774 17.178 KCNH6|potassium voltage-gated channel, subfamily H (eag-related), member 6 -26958 (+) DCAF7|DDB1 and CUL4 associated factor 7 144 (+)

36:0.846

chr11:67275695..67275840 17.008 CDK2AP2|cyclin-dependent kinase 2 associated protein 2 -134 (-) CDK2AP2|cyclin-dependent kinase 2 associated protein 2 372 (-)

18:0.856, -21:0.799

chr17:38574229..38574395 16.975 TOP2A|topoisomerase (DNA) II alpha 170kDa -188 (-) IGFBP4|insulin-like growth factor binding protein 4 25507 (+)

-4:0.499, -71:0.442, 79:0.972

chr19:7894814..7894976 16.961 CLEC4M|C-type lectin domain family 4, member M -66802 (+) EVI5L|ecotropic viral integration site 5-like 281 (+)

-43:0.521

chr19:12662360..12662504 16.890 ZNF564|zinc finger protein 564 -159 (-) ZNF490|zinc finger protein 490 59129 (-)

-86:0.826

chr19:54641214..54641398 16.871 PRPF31|PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) -22127 (+) CNOT3|CCR4-NOT transcription complex, subunit 3 141 (+)

47:0.755

chr17:79818616..79818771 16.750 P4HB|prolyl 4-hydroxylase, beta polypeptide -156 (-) ARHGDIA|Rho GDP dissociation inhibitor (GDI) alpha 10047 (-)

-17:0.988, 98:0.893

chr17:4870610..4870782 16.658 ENO3|enolase 3 (beta, muscle) -16292 (+) SPAG7|sperm associated antigen 7 415 (-)

-31:0.746, -71:0.370

chr19:13905997..13906148 16.499 C19orf53|chromosome 19 open reading frame 53 -20788 (+) ZSWIM4|zinc finger, SWIM-type containing 4 173 (+)

-42:0.988, 87:0.340

chr19:36193319..36193457 16.496 UPK1A|uroplakin 1A -35672 (+) ZBTB32|zinc finger and BTB domain containing 32 10441 (+)

-22:0.986, 33:0.242, 94:0.966

chr19:47551913..47552033 16.443 TMEM160|transmembrane protein 160 -77 (-) ZC3H4|zinc finger CCCH-type containing 4 63513 (-)

-10:0.573, 31:0.223

chr9:140135525..140135676 16.392 SLC34A3|solute carrier family 34 (sodium phosphate), member 3 -10216 (+) TUBB4B|tubulin, beta 4B class IVb 108 (+)

-23:0.306

chr8:145159238..145159356 16.212 SHARPIN|SHANK-associated RH domain interactor -146 (-) MAF1|MAF1 homolog (S. cerevisiae) 47 (+)

-77:0.558

chr12:57039840..57039982 16.146 ATP5B|ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide -85 (-) PTGES3|prostaglandin E synthase 3 (cytosolic) 41939 (-)

40:0.626

chr19:42772981..42773165 16.104 ERF|Ets2 repressor factor -13768 (-) CIC|capicua homolog (Drosophila) 15656 (+)

-42:0.540, -82:0.266

chr19:10828452..10828636 16.037 QTRT1|queuine tRNA-ribosyltransferase 1 -16386 (+) DNM2|dynamin 2 188 (+)

0:0.325, 100:0.921

chr19:4342840..4342997 15.999 STAP2|signal transducing adaptor family member 2 -168 (-) MPND|MPN domain containing 641 (+)

-27:0.620, 49:0.227, -51:0.798, 83:0.564

chr14:96001104..96001269 15.964 SNHG10|small nucleolar RNA host gene 10 (non-protein coding) -171 (-) GLRX5|glutaredoxin 5 140 (+)

109:0.257

chr19:15529839..15529998 15.861 AKAP8L|A kinase (PRKA) anchor protein 8-like -84 (-) WIZ|widely interspaced zinc finger motifs 13627 (-)

87:0.312

chr1:206138208..206138393 15.859 LOC100132966|uncharacterized LOC100132966 -852 (-) FAM72A|family with sequence similarity 72, member A FAM72B|family with sequence similarity 72, member B 616 (+)

-16:0.582, -47:0.770

chr1:120838743..120838928 15.847 NOTCH2|notch 2 -226520 (-) FAM72B|family with sequence similarity 72, member B 169 (+)

-54:0.770

chr19:6424941..6425116 15.840 KHSRP|KH-type splicing regulatory protein -206 (-) SLC25A41|solute carrier family 25, member 41 8752 (-)

-63:0.971

chr19:42773250..42773375 15.825 ERF|Ets2 repressor factor -14007 (-) CIC|capicua homolog (Drosophila) 15417 (+)

57:0.966

chr19:6425242..6425424 15.713 KHSRP|KH-type splicing regulatory protein -511 (-) SLC25A41|solute carrier family 25, member 41 8447 (-)

-94:0.397

chr17:79212906..79213057 15.663 C17orf56|chromosome 17 open reading frame 56 -92 (-) C17orf89|chromosome 17 open reading frame 89 153 (+)

-5:0.498

chr1:143913327..143913512 15.612 FAM72D|family with sequence similarity 72, member D -289 (-) PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4C|peptidylprolyl isomerase A (cyclophilin A)-like 4C PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G 450805 (-)

48:0.468, -71:0.770

chr7:106809257..106809398 15.602 PRKAR2B|protein kinase, cAMP-dependent, regulatory, type II, beta -124124 (+) HBP1|HMG-box transcription factor 1 112 (+)

49:0.918, -94:0.222

chr9:139780736..139780861 15.565 EDF1|endothelial differentiation-related factor 1 -20060 (-) TRAF2|TNF receptor-associated factor 2 155 (+)

-4:0.221, -38:0.789

chr14:21737674..21737818 15.504 HNRNPC|heterogeneous nuclear ribonucleoprotein C (C1/C2) -175 (-) RPGRIP1|retinitis pigmentosa GTPase regulator interacting protein 1 18389 (+)

-25:0.830, 82:0.920, -93:0.965

chr1:151763080..151763252 15.419 TDRKH|tudor and KH domain containing -196 (-) 98 (+)

10:0.862, 73:0.324

chr19:6737680..6737831 15.371 GPR108|G protein-coupled receptor 108 -137 (-) TRIP10|thyroid hormone receptor interactor 10 1979 (+)

-54:0.938, -104:0.593

chr19:10828308..10828427 15.307 QTRT1|queuine tRNA-ribosyltransferase 1 -16209 (+) DNM2|dynamin 2 365 (+)

1:0.949

chr19:37808566..37808727 15.189 ZNF383|zinc finger protein 383 -91281 (+) HKR1|HKR1, GLI-Kruppel zinc finger family member 179 (+)

-23:0.985, 111:0.904

chr14:104181817..104181948 14.983 XRCC3|X-ray repair complementing defective repair in Chinese hamster cells 3 -99 (-) ZFYVE21|zinc finger, FYVE domain containing 21 234 (+)

-28:0.685

chr15:89631446..89631607 14.957 ABHD2|abhydrolase domain containing 2 -146 (+) ABHD2|abhydrolase domain containing 2 122 (+)

chr20:32308110..32308260 14.868 PXMP4|peroxisomal membrane protein 4, 24kDa -171 (-) ZNF341|zinc finger protein 341 11611 (+)

-23:0.981, 60:0.952

chr2:27008668..27008825 14.864 C2orf18|chromosome 2 open reading frame 18 CENPA|centromere protein A -21577 (+) CENPA|centromere protein A 146 (+)

-26:0.349, 48:0.976

chr19:2945001..2945107 14.786 ZNF77|zinc finger protein 77 -111 (-) TLE6|transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila) 32512 (+)

-35:0.959, 68:0.959, 106:0.826

chr2:88927129..88927302 14.703 EIF2AK3|eukaryotic translation initiation factor 2-alpha kinase 3 -237 (-) RPIA|ribose 5-phosphate isomerase A 64000 (+)

chr7:44887893..44888034 14.609 H2AFV|H2A histone family, member V -237 (-) PURB|purine-rich element binding protein B 37006 (-)

-14:0.921, -45:0.809

chr17:74667855..74668000 14.377 ST6GALNAC1|ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 -28121 (-) MXRA7|matrix-remodelling associated 7 39105 (-)

60:0.364

chr5:139781055..139781217 14.353 -95 (-) ANKHD1-EIF4EBP3|ANKHD1-EIF4EBP3 readthrough ANKHD1|ankyrin repeat and KH domain containing 1 261 (+)

63:0.298

chr5:151151258..151151443 14.276 LOC100652758|uncharacterized LOC100652758 -377 (-) G3BP1|GTPase activating protein (SH3 domain) binding protein 1 122 (+)

11:0.744, -63:0.344

chr12:56367552..56367737 14.247 CDK2|cyclin-dependent kinase 2 -7055 (+) RAB5B|RAB5B, member RAS oncogene family 118 (+)

21:0.291

chr19:4246936..4247073 14.149 EBI3|Epstein-Barr virus induced 3 -17484 (+) CCDC94|coiled-coil domain containing 94 86 (+)

-6:0.902, 25:0.587

chr19:4968723..4968907 14.115 -51987 (-) KDM4B|lysine (K)-specific demethylase 4B 309 (+)

44:0.301

chr19:4472050..4472177 14.113 UBXN6|UBX domain protein 6 -14324 (-) HDGFRP2|hepatoma-derived growth factor-related protein 2 234 (+)

-22:0.954

chr19:42901131..42901279 14.061 CNFN|cornifelin -6774 (-) 107 (+)

-49:0.475

chr22:40440627..40440763 13.988 FAM83F|family with sequence similarity 83, member F -49751 (+) TNRC6B|trinucleotide repeat containing 6B 214 (+)

-47:0.862

chr19:17377946..17378103 13.914 USHBP1|Usher syndrome 1C binding protein 1 -2477 (-) BABAM1|BRISC and BRCA1 A complex member 1 181 (+)

21:0.317, 53:0.618

chr1:43312112..43312233 13.860 ERMAP|erythroblast membrane-associated protein (Scianna blood group) -20902 (+) ZNF691|zinc finger protein 691 78 (+)

22:0.839

chr12:53773362..53773546 13.811 SP7|Sp7 transcription factor -43451 (-) SP1|Sp1 transcription factor 536 (+)

66:0.989, -104:0.740

chr22:38054356..38054512 13.807 SH3BP1|SH3-domain binding protein 1 -18675 (+) PDXP|pyridoxal (pyridoxine, vitamin B6) phosphatase 311 (+)

7:0.977, -44:0.993

chr1:6845206..6845359 13.783 DNAJC11|DnaJ (Hsp40) homolog, subfamily C, member 11 -83351 (-) CAMTA1|calmodulin binding transcription activator 1 209 (+)

-49:0.705

chr1:6052577..6052705 13.778 NPHP4|nephronophthisis 4 -132 (-) KCNAB2|potassium voltage-gated channel, shaker-related subfamily, beta member 2 85 (+)

15:0.256, -38:0.755, 46:0.993, -81:0.994

chr1:151254512..151254677 13.713 ZNF687|zinc finger protein 687 -552 (+) ZNF687|zinc finger protein 687 179 (+)

-47:0.781

chr9:37465687..37465872 13.679 ZBTB5|zinc finger and BTB domain containing 5 -338 (-) POLR1E|polymerase (RNA) I polypeptide E, 53kDa 20251 (+)

-3:0.939, 47:0.266

chr19:18315084..18315200 13.672 RAB3A|RAB3A, member RAS oncogene family -338 (-) PDE4C|phosphodiesterase 4C, cAMP-specific 20160 (-)

-2:0.994

chr2:73460425..73460544 13.656 PRADC1|protease-associated domain containing 1 -120 (-) CCT7|chaperonin containing TCP1, subunit 7 (eta) 915 (+)

18:0.898

chr12:14927151..14927276 13.555 HIST4H4|histone cluster 4, H4 -3172 (-) H2AFJ|H2A histone family, member J 72 (+)

47:0.763, 64:0.839

chr19:18303745..18303929 13.514 IFI30|interferon, gamma-inducible protein 30 -19196 (+) MPV17L2|MPV17 mitochondrial membrane protein-like 2 198 (+)

-21:0.949, 41:0.812

chr19:19174380..19174540 13.485 ARMC6|armadillo repeat containing 6 -29800 (+) SLC25A42|solute carrier family 25, member 42 349 (+)

chr9:131843085..131843265 13.474 FAM73B|family with sequence similarity 73, member B -43943 (+) DOLPP1|dolichyl pyrophosphate phosphatase 1 220 (+)

-11:0.988, -59:0.993, 71:0.329

chr2:71454254..71454403 13.449 PAIP2B|poly(A) binding protein interacting protein 2B -98 (-) ZNF638|zinc finger protein 638 49398 (+)

19:0.786, 74:0.989

chr22:35696129..35696255 13.410 TOM1|target of myb1 (chicken) -296 (+) HMOX1|heme oxygenase (decycling) 1 80876 (+)

chr19:33462937..33463061 13.401 CEP89|centrosomal protein 89kDa -156 (-) C19orf40|chromosome 19 open reading frame 40 171 (+)

-50:0.981, 50:0.961, -75:0.426

chr7:27702580..27702717 13.399 HIBADH|3-hydroxyisobutyrate dehydrogenase -71 (-) TAX1BP1|Tax1 (human T-cell leukemia virus type I) binding protein 1 76343 (+)

-8:0.978, 28:0.961

chr5:145826719..145826864 13.349 POU4F3|POU class 4 homeobox 3 -108161 (+) TCERG1|transcription elongation regulator 1 103 (+)

77:0.970

chr11:66056638..66056821 13.335 YIF1A|Yip1 interacting factor homolog A (S. cerevisiae) -105 (-) TMEM151A|transmembrane protein 151A 2609 (+)

73:0.851, -97:0.811

chr20:44486078..44486182 13.306 ACOT8|acyl-CoA thioesterase 8 -121 (-) ZSWIM3|zinc finger, SWIM-type containing 3 110 (+)

-36:0.446

chr19:48972330..48972509 13.271 KCNJ14|potassium inwardly-rectifying channel, subfamily J, member 14 -7914 (+) CYTH2|cytohesin 2 99 (+)

12:0.972, -58:0.301

chr1:154955675..154955805 13.210 CKS1B|CDC28 protein kinase regulatory subunit 1B -8509 (+) FLAD1|FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae) 63 (+)

chr12:54718751..54718892 13.210 NFE2|nuclear factor (erythroid-derived 2), 45kDa -24014 (-) COPZ1|coatomer protein complex, subunit zeta 1 91 (+)

73:0.934

chr9:34989471..34989655 13.206 KIAA1045|KIAA1045 -31240 (+) DNAJB5|DnaJ (Hsp40) homolog, subfamily B, member 5 154 (+)

-41:0.218

chr11:125462549..125462699 13.200 EI24|etoposide induced 2.4 mRNA -23217 (+) STT3A|STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) 114 (+)

chr16:1832631..1832815 13.159 SPSB3|splA/ryanodine receptor domain and SOCS box containing 3 -131 (-) NUBP2|nucleotide binding protein 2 236 (+)

-6:0.898

chr19:1041053..1041190 13.154 ABCA7|ATP-binding cassette, sub-family A (ABC1), member 7 -987 (+) HMHA1|histocompatibility (minor) HA-1 26022 (+)

-2:0.929, 31:0.956

chr16:57769234..57769374 13.104 CCDC135|coiled-coil domain containing 135 -40575 (+) KATNB1|katanin p80 (WD repeat containing) subunit B 1 341 (+)

4:0.899, -38:0.967

chr19:36248846..36248962 13.085 HSPB6|heat shock protein, alpha-crystallin-related, B6 -973 (-) C19orf55|chromosome 19 open reading frame 55 173 (+)

-60:0.285, 70:0.821

chr1:110881830..110882015 12.955 KCNC4|potassium voltage-gated channel, Shaw-related subfamily, member 4 -127925 (+) RBM15|RNA binding motif protein 15 72 (+)

-26:0.337, 106:0.809

chr19:14228600..14228721 12.945 PRKACA|protein kinase, cAMP-dependent, catalytic, alpha -91 (-) ASF1B|ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 18672 (-)

-18:0.946, -61:0.878

chr19:50269732..50269916 12.887 TSKS|testis-specific serine kinase substrate -3296 (-) AP2A1|adaptor-related protein complex 2, alpha 1 subunit 327 (+)

44:0.444

chr19:45873883..45874006 12.844 ERCC2|excision repair cross-complementing rodent repair deficiency, complementation group 2 -99 (-) PPP1R13L|protein phosphatase 1, regulatory subunit 13 like 34369 (-)

4:0.875, 97:0.924

chr14:94492590..94492686 12.843 ASB2|ankyrin repeat and SOCS box containing 2 -49562 (-) OTUB2|OTU domain, ubiquitin aldehyde binding 2 65 (+)

chr4:52709021..52709158 12.827 CWH43|cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) -3720817 (+) DCUN1D4|DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae) 197 (+)

chrX:49047673..49047857 12.827 PRICKLE3|prickle homolog 3 (Drosophila) -4911 (-) 125 (+)

-13:0.744, 57:0.980

chr19:41769874..41770056 12.822 HNRNPUL1|heterogeneous nuclear ribonucleoprotein U-like 1 -1498 (+) HNRNPUL1|heterogeneous nuclear ribonucleoprotein U-like 1 184 (+)

8:0.415, 38:0.641, -80:0.439

chr3:88108203..88108318 12.820 CGGBP1|CGG triplet repeat binding protein 1 -117 (-) ZNF654|zinc finger protein 654 80001 (+)

chr19:39340661..39340845 12.807 HNRNPL|heterogeneous nuclear ribonucleoprotein L -128 (-) HNRNPL|heterogeneous nuclear ribonucleoprotein L 2223 (-)

-9:0.659

chrX:49125622..49125807 12.772 FOXP3|forkhead box P3 -4485 (-) PPP1R3F|protein phosphatase 1, regulatory subunit 3F 589 (+)

-25:0.423, 25:0.486, -77:0.908, 88:0.781

chr1:206137850..206138035 12.731 LOC100132966|uncharacterized LOC100132966 -494 (-) FAM72A|family with sequence similarity 72, member A FAM72B|family with sequence similarity 72, member B 974 (+)

-50:0.965

chr2:97523816..97523943 12.731 ANKRD39|ankyrin repeat domain 39 -137 (-) SEMA4C|sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 11752 (-)

chr1:150601634..150601792 12.716 ENSA|endosulfine alpha -131 (-) ENSA|endosulfine alpha 216 (-)

-30:0.891

chr14:23755389..23755526 12.620 HOMEZ|homeobox and leucine zipper encoding -132 (-) BCL2L2-PABPN1|BCL2L2-PABPN1 readthrough BCL2L2|BCL2-like 2 20587 (+)

-18:0.388

chr2:44395513..44395689 12.616 LRPPRC|leucine-rich PPR-motif containing -172462 (-) PPM1B|protein phosphatase, Mg2+/Mn2+ dependent, 1B 414 (+)

-40:0.954

chr11:13299045..13299189 12.589 RASSF10|Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 -268193 (+) ARNTL|aryl hydrocarbon receptor nuclear translocator-like 175 (+)

35:0.287, 81:0.664

chr3:126422969..126423075 12.571 TXNRD3|thioredoxin reductase 3 -49046 (-) CHCHD6|coiled-coil-helix-coiled-coil-helix domain containing 6 55 (+)

chr19:55851070..55851208 12.520 TMEM150B|transmembrane protein 150B -14450 (-) SUV420H2|suppressor of variegation 4-20 homolog 2 (Drosophila) 121 (+)

-8:0.946, 44:0.710

chr16:74700813..74700972 12.513 RFWD3|ring finger and WD repeat domain 3 -115 (-) MLKL|mixed lineage kinase domain-like 33845 (-)

18:0.988, -64:0.824

chr19:54663563..54663741 12.500 LENG1|leukocyte receptor cluster (LRC) member 1 -194 (-) TMC4|transmembrane channel-like 4 13226 (-)

19:0.616, 63:0.510, -70:0.219

chr16:89557178..89557337 12.492 ANKRD11|ankyrin repeat domain 11 -326 (-) SPG7|spastic paraplegia 7 (pure and complicated autosomal recessive) 17557 (+)

chr17:57232597..57232775 12.465 SKA2|spindle and kinetochore associated complex subunit 2 -140 (-) SKA2|spindle and kinetochore associated complex subunit 2 113 (-)

-56:0.789, 77:0.839

chr19:55973067..55973242 12.441 ISOC2|isochorismatase domain containing 2 -99 (-) ZNF628|zinc finger protein 628 14544 (+)

-78:0.203

chr19:17420202..17420342 12.417 MRPL34|mitochondrial ribosomal protein L34 -3681 (+) DDA1|DET1 and DDB1 associated 1 9 (+)

0:0.754, -29:0.792

chr17:73452571..73452700 12.383 GRB2|growth factor receptor-bound protein 2 -50832 (-) KIAA0195|KIAA0195 103 (+)

-19:0.985, 20:0.495

chr1:150669761..150669920 12.363 GOLPH3L|golgi phosphoprotein 3-like -255 (-) HORMAD1|HORMA domain containing 1 23502 (-)

-16:0.333, 47:0.966

chr22:20004397..20004514 12.355 ARVCF|armadillo repeat gene deleted in velocardiofacial syndrome -132 (-) C22orf25|chromosome 22 open reading frame 25 4162 (+)

-46:0.904

chr8:42010303..42010433 12.354 KAT6A|K(lysine) acetyltransferase 6A -100869 (-) AP3M2|adaptor-related protein complex 3, mu 2 subunit 165 (+)

24:0.804

chr3:114866146..114866331 12.325 ZBTB20|zinc finger and BTB domain containing 20 -124 (-) GAP43|growth associated protein 43 475912 (+)

-14:0.986

chr4:331425..331558 12.296 ZNF732|zinc finger protein 732 -41548 (-) ZNF141|zinc finger protein 141 104 (+)

34:0.890

chr6:136571472..136571636 12.291 FAM54A|family with sequence similarity 54, member A -125 (-) BCLAF1|BCL2-associated transcription factor 1 39356 (-)

-16:0.978, 64:0.970

chr2:232645999..232646133 12.248 PDE6D|phosphodiesterase 6D, cGMP-specific, rod, delta -141 (-) COPS7B|COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) 371 (+)

-29:0.767

chr20:17662929..17663062 12.242 RRBP1|ribosome binding protein 1 homolog 180kDa (dog) -112 (-) BANF2|barrier to autointegration factor 2 11324 (+)

-15:0.904, 90:0.946

chr1:120838359..120838543 12.225 NOTCH2|notch 2 -226136 (-) FAM72B|family with sequence similarity 72, member B 553 (+)

-30:0.965

chr16:30381966..30382151 12.181 TBC1D10B|TBC1 domain family, member 10B -534 (-) MYLPF|myosin light chain, phosphorylatable, fast skeletal muscle 4052 (+)

1:0.755, 33:0.220, -47:0.981

chr15:90895365..90895490 12.175 NGRN|neugrin, neurite outgrowth associated -86507 (+) ZNF774|zinc finger protein 774 96 (+)

28:0.774

chr19:39340963..39341147 12.175 HNRNPL|heterogeneous nuclear ribonucleoprotein L -430 (-) HNRNPL|heterogeneous nuclear ribonucleoprotein L 1921 (-)

51:0.699, -90:0.821, 113:0.979

chr19:41082647..41082774 12.137 SPTBN4|spectrin, beta, non-erythrocytic 4 -46279 (+) SHKBP1|SH3KBP1 binding protein 1 39 (+)

chr1:10458961..10459090 12.121 KIF1B|kinesin family member 1B -188254 (+) PGD|phosphogluconate dehydrogenase 104 (+)

29:0.325

chr1:33502509..33502643 12.121 AK2|adenylate kinase 2 -76 (-) ADC|arginine decarboxylase 44157 (+)

58:0.778

chr22:39101512..39101696 12.068 JOSD1|Josephin domain containing 1 -5380 (-) GTPBP1|GTP binding protein 1 261 (+)

-8:0.708

chr14:23938582..23938725 12.038 MYH7|myosin, heavy chain 7, cardiac muscle, beta -33794 (-) NGDN|neuroguidin, EIF4E binding protein 238 (+)

-11:0.987, -53:0.608

chr14:78083185..78083349 12.036 SPTLC2|serine palmitoyltransferase, long chain base subunit 2 -141 (-) ALKBH1|alkB, alkylation repair homolog 1 (E. coli) 91085 (-)

-44:0.546

chr22:37172180..37172348 12.024 IFT27|intraflagellar transport 27 homolog (Chlamydomonas) -109 (-) PVALB|parvalbumin 43255 (-)

-20:0.909, -68:0.476

chr2:74685350..74685506 12.014 INO80B|INO80 complex subunit B -3224 (+) WBP1|WW domain binding protein 1 199 (+)

83:0.933

chr7:150725390..150725510 11.987 ATG9B|ATG9 autophagy related 9 homolog B (S. cerevisiae) -3882 (-) ABCB8|ATP-binding cassette, sub-family B (MDR/TAP), member 8 113 (+)

chr19:19174637..19174762 11.977 ARMC6|armadillo repeat containing 6 -30039 (+) SLC25A42|solute carrier family 25, member 42 110 (+)

-23:0.260, 56:0.891

chr7:8008243..8008383 11.973 RPA3|replication protein A3, 14kDa -250076 (-) GLCCI1|glucocorticoid induced transcript 1 120 (+)

33:0.839, -37:0.556

chr12:112563211..112563321 11.949 NAA25|N(alpha)-acetyltransferase 25, NatB auxiliary subunit -16668 (-) TRAFD1|TRAF-type zinc finger domain containing 1 56 (+)

24:0.751, -54:0.675

chr12:58087732..58087916 11.937 B4GALNT1|beta-1,4-N-acetyl-galactosaminyl transferase 1 -60880 (-) OS9|osteosarcoma amplified 9, endoplasmic reticulum lectin 16 (+)

33:0.524, -77:0.432, -96:0.340

chr5:32313280..32313404 11.934 MTMR12|myotubularin related protein 12 -209 (-) ZFR|zinc finger RNA binding protein 75278 (-)

-72:0.988

chr10:76586193..76586332 11.923 ADK|adenosine kinase -649675 (+) KAT6B|K(lysine) acetyltransferase 6B 92 (+)

chr16:58663824..58663962 11.876 CNOT1|CCR4-NOT transcription complex, subunit 1 -148 (-) SLC38A7|solute carrier family 38, member 7 54763 (-)

-56:0.426

chr20:44441097..44441208 11.849 DNTTIP1|deoxynucleotidyltransferase, terminal, interacting protein 1 -20521 (+) UBE2C|ubiquitin-conjugating enzyme E2C 129 (+)

41:0.242, 72:0.290

chrX:3732929..3733089 11.758 PRKX|protein kinase, X-linked -101291 (-) NLGN4X|neuroligin 4, X-linked 2412878 (-)

chr5:31532240..31532381 11.731 DROSHA|drosha, ribonuclease type III -88 (-) C5orf22|chromosome 5 open reading frame 22 125 (+)

chr11:65382939..65383070 11.722 MAP3K11|mitogen-activated protein kinase kinase kinase 11 -228 (-) PCNXL3|pecanex-like 3 (Drosophila) 702 (+)

chr17:47841565..47841750 11.719 FAM117A|family with sequence similarity 117, member A -111 (-) KAT7|K(lysine) acetyltransferase 7 24361 (+)

65:0.923, -88:0.595, 106:0.486

chr19:8455123..8455245 11.699 ANGPTL4|angiopoietin-like 4 -26077 (+) RAB11B|RAB11B, member RAS oncogene family 35 (+)

-25:0.994

chr1:35658790..35658949 11.687 SFPQ|splicing factor proline/glutamine-rich -124 (-) ZMYM4|zinc finger, MYM-type 4 75693 (+)

11:0.933

chrX:47420437..47420583 11.684 ZNF41|zinc finger protein 41 -78166 (-) ARAF|v-raf murine sarcoma 3611 viral oncogene homolog 57 (+)

46:0.494

chr4:775614..775733 11.682 LOC100129917|uncharacterized LOC100129917 -51 (-) CPLX1|complexin 1 44252 (-)

-16:0.981, 48:0.966

chr12:120638946..120639084 11.651 RPLP0|ribosomal protein, large, P0 -53 (-) PXN|paxillin 48944 (-)

-25:0.459, -54:0.993

chr15:93425638..93425770 11.636 FAM174B|family with sequence similarity 174, member B -148315 (-) CHD2|chromodomain helicase DNA binding protein 2 17782 (+)

34:0.227

chr4:52709165..52709271 11.633 CWH43|cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) -3720946 (+) DCUN1D4|DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae) 68 (+)

53:0.385

chr19:55850794..55850957 11.609 TMEM150B|transmembrane protein 150B -14186 (-) SUV420H2|suppressor of variegation 4-20 homolog 2 (Drosophila) 385 (+)

68:0.652

chr7:77427850..77427996 11.599 TMEM60|transmembrane protein 60 -176 (-) PHTF2|putative homeodomain transcription factor 2 218 (+)

chr17:7475890..7476026 11.556 SENP3|SUMO1/sentrin/SMT3 specific peptidase 3 -10529 (+) EIF4A1|eukaryotic translation initiation factor 4A1 134 (+)

chr8:47368577..47368662 11.516 POTEA|POTE ankyrin domain family, member A -4221014 (+) KIAA0146|KIAA0146 804876 (+)

chr10:5932012..5932132 11.500 ANKRD16|ankyrin repeat domain 16 -216 (-) FBXO18|F-box protein, helicase, 18 127 (+)

32:0.689

chr11:105893162..105893305 11.475 KIAA1826|KIAA1826 -274 (-) AASDHPPT|aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 55132 (+)

chr14:73925284..73925415 11.415 NUMB|numb homolog (Drosophila) -58 (-) C14orf169|chromosome 14 open reading frame 169 32276 (+)

3:0.990

chr17:1619644..1619800 11.406 MIR22HG|MIR22 host gene (non-protein coding) -234 (-) WDR81|WD repeat domain 81 133 (+)

33:0.332, -38:0.330

chr15:75531972..75532149 11.383 C15orf39|chromosome 15 open reading frame 39 -37817 (+) GOLGA6A|golgin A6 family, member A GOLGA6C|golgin A6 family, member C 18838 (+)

17:0.650, -23:0.210, 58:0.650, -60:0.650, -101:0.650

chr3:107241683..107241798 11.363 CCDC54|coiled-coil domain containing 54 -145430 (+) BBX|bobby sox homolog (Drosophila) 109 (+)

24:0.683

chr2:73298466..73298593 11.357 SFXN5|sideroflexin 5 -93 (-) SFXN5|sideroflexin 5 360 (-)

0:0.933, 42:0.904, -69:0.909

chr19:19496325..19496445 11.329 -64721 (+) GATAD2A|GATA zinc finger domain containing 2A 321 (+)

chr12:113658900..113659035 11.328 IQCD|IQ motif containing D -105 (-) TPCN1|two pore segment channel 1 276 (+)

3:0.978

chrX:58377736..58377828 11.313 ZXDA|zinc finger, X-linked, duplicated A -440823 (-) SPIN4|spindlin family, member 4 4193417 (-)

chr16:30382259..30382443 11.300 TBC1D10B|TBC1 domain family, member 10B -827 (-) MYLPF|myosin light chain, phosphorylatable, fast skeletal muscle 3759 (+)

40:0.208, 98:0.972

chr1:143913146..143913271 11.289 FAM72D|family with sequence similarity 72, member D -78 (-) PPIAL4A|peptidylprolyl isomerase A (cyclophilin A)-like 4A PPIAL4B|peptidylprolyl isomerase A (cyclophilin A)-like 4B PPIAL4C|peptidylprolyl isomerase A (cyclophilin A)-like 4C PPIAL4G|peptidylprolyl isomerase A (cyclophilin A)-like 4G 451016 (-)

chr1:153895512..153895680 11.261 GATAD2B|GATA zinc finger domain containing 2B -145 (-) DENND4B|DENN/MADD domain containing 4B 23550 (-)

chr20:40247058..40247168 11.255 CHD6|chromodomain helicase DNA binding protein 6 -52 (-) PTPRT|protein tyrosine phosphatase, receptor type, T 1571397 (-)

chr10:104005062..104005229 11.251 PITX3|paired-like homeodomain 3 -3916 (-) GBF1|golgi brefeldin A resistant guanine nucleotide exchange factor 1 134 (+)

45:0.218, -84:0.880, 87:0.748

chr19:8454926..8455097 11.230 ANGPTL4|angiopoietin-like 4 -25904 (+) RAB11B|RAB11B, member RAS oncogene family 208 (+)

chr19:36119753..36119917 11.223 HAUS5|HAUS augmin-like complex, subunit 5 -16164 (+) RBM42|RNA binding motif protein 42 107 (+)

19:0.988, 57:0.870

chr9:139743695..139743839 11.223 PHPT1|phosphohistidine phosphatase 1 -273 (+) PHPT1|phosphohistidine phosphatase 1 100 (+)

-44:0.695

chr8:11659977..11660133 11.206 NEIL2|nei endonuclease VIII-like 2 (E. coli) -32787 (+) FDFT1|farnesyl-diphosphate farnesyltransferase 1 129 (+)

67:0.934

chr19:19030302..19030474 11.204 COPE|coatomer protein complex, subunit epsilon -188 (-) DDX49|DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 92 (+)

-25:0.738, 67:0.366

chr19:50180319..50180451 11.200 BCL2L12|BCL2-like 12 (proline rich) -11198 (+) PRMT1|protein arginine methyltransferase 1 64 (+)

chr19:58892612..58892741 11.196 ZNF837|zinc finger protein 837 -260 (-) RPS5|ribosomal protein S5 5976 (+)

chr12:53473198..53473319 11.173 SPRYD3|SPRY domain containing 3 -71 (-) IGFBP6|insulin-like growth factor binding protein 6 18169 (+)

12:0.983, -27:0.960

chr18:71959280..71959412 11.145 CYB5A|cytochrome b5 type A (microsomal) -167 (-) C18orf63|chromosome 18 open reading frame 63 23763 (+)

chr15:64673712..64673847 11.134 KIAA0101|KIAA0101 -144 (-) TRIP4|thyroid hormone receptor interactor 4 6257 (+)

-59:0.956

chr14:105957345..105957520 11.131 C14orf80|chromosome 14 open reading frame 80 -913 (+) C14orf80|chromosome 14 open reading frame 80 204 (+)

0:0.206

chr14:23790521..23790634 11.130 PABPN1|poly(A) binding protein, nuclear 1 -1181 (+) PABPN1|poly(A) binding protein, nuclear 1 97 (+)

chr16:70323442..70323541 11.120 AARS|alanyl-tRNA synthetase -80 (-) DDX19B|DEAD (Asp-Glu-Ala-As) box polypeptide 19B 9585 (+)

-34:0.959

chr19:2841336..2841459 11.051 ZNF554|zinc finger protein 554 -21392 (+) ZNF555|zinc finger protein 555 61 (+)

-13:0.497, 18:0.952, -87:0.740

chr16:4852920..4853039 11.014 -81 (-) GLYR1|glyoxylate reductase 1 homolog (Arabidopsis) 1924 (-)

8:0.652, 47:0.626

chr1:11322674..11322822 10.985 MTOR|mechanistic target of rapamycin (serine/threonine kinase) -141 (-) UBIAD1|UbiA prenyltransferase domain containing 1 10568 (+)

-64:0.204, -105:0.360

chr18:14132447..14132599 10.982 ZNF519|zinc finger protein 519 -66 (-) ANKRD20A5P|ankyrin repeat domain 20 family, member A5, pseudogene 46786 (+)

-7:0.848

chr14:68286385..68286520 10.960 ZFYVE26|zinc finger, FYVE domain containing 26 -3153 (-) RAD51B|RAD51 homolog B (S. cerevisiae) 68 (+)

0:0.979

chr1:24742143..24742307 10.943 C1orf201|chromosome 1 open reading frame 201 -639 (-) NIPAL3|NIPA-like domain containing 3 78 (+)

chr15:43213053..43213183 10.935 TTBK2|tau tubulin kinase 2 -136 (-) UBR1|ubiquitin protein ligase E3 component n-recognin 1 185121 (-)

chr1:153940187..153940323 10.931 SLC39A1|solute carrier family 39 (zinc transporter), member 1 -68 (-) CREB3L4|cAMP responsive element binding protein 3-like 4 119 (+)

chr5:43313807..43313940 10.918 HMGCS1|3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -277 (-) CCL28|chemokine (C-C motif) ligand 28 83353 (-)

-30:0.260, 30:0.403

Examples of peaks fitted within regions

Complementary Motifs Enriched In Peaks:

Motif Name

Sequence Logo

Motif Ensemble Enrichment (Motif Ensemble log-Likelihood Ratio)

Enrichment (log-Likelihood Ratio)

Precision and Recall

Prediction - Observation Correlation

Enrichment at Binding Sites

Number of Positively Predicted Peaks

denovo_WM_21 24.107 (1591.26) 24.107 (1591.26) 0.8348 0.257 3.4221 940/1464

Contribution and Correlation Plots

Top Motifs Enriched In Peaks:

Motif Name

Sequence Logo

Enrichment (log-Likelihood Ratio)

Precision and Recall

Prediction - Observation Correlation

Enrichment at Binding Sites

Number of Positively Predicted Peaks

denovo_WM_21 24.107 (1591.26) 0.8348 0.257 3.4221 940/1464
denovo_WM_15 23.392 (1576.198) 0.8263 0.2472 3.433 885/1464
HCMC.NFYB_f1.wm 19.903 (1495.425) 0.8668 0.281 3.2635 1158/1464
HCMC.NFYA_f1.wm 18.584 (1461.154) 0.8770 0.2984 3.2646 1185/1464
denovo_WM_7 18.456 (1457.706) 0.8785 0.3268 3.3062 1193/1464
denovo_WM_5 17.045 (1417.938) 0.8831 0.3463 3.2987 1211/1464
JASPAR.NFYA.wm 16.77 (1409.794) 0.8742 0.2814 3.2463 1198/1464
denovo_WM_16 15.184 (1360.107) 0.8901 0.3459 3.2369 1237/1464
denovo_WM_22 14.837 (1348.563) 0.8901 0.3473 3.2307 1242/1464
denovo_WM_8 14.53 (1338.109) 0.8903 0.3482 3.2228 1242/1464

Downloads

IRF3 Replicate 1

IRF3 Replicate 2

BG Replicate 1

BG Replicate 2