CRUNCH Results

QC summary table

QC statistics for this dataset

Comparison with ENCODE datasets

Mapping

Fraction of mapped reads for the IP samples:
0.838
69th percentile
Fraction of mapped reads for the background samples:
0.890
78th percentile

ChIP enrichment signal

Noise level ChIP signal:
0.126
`
13th percentile
Error in fit of enrichment distribution:
0.364
13th percentile

Peak statistics

Number of peaks:
44017
89th percentile
Fraction of reads mapped to peaks:
0.056
77th percentile

Motif enrichment statistics

Enrichment of top motif:
81.40
95th percentile
Enrichment of complimentary motif set:
81.40
95th percentile

Quality Control, Mapping, Fragment Size Estimation:

SMC3 Replicate 1

fragment size plot

SMC3 Replicate 2

fragment size plot

BG Replicate 1

fragment size plot

BG Replicate 2

fragment size plot

Peak Calling:

zvalue histogram reverse cumulative of zvalues

Top peaks:


Coordinates Z-score Nearest Genes on the Left Offset of Nearest TSS on the Left (Strand) Nearest Genes on the Right Offset of Nearest TSS on the Right (Strand) CTCF.p2
chr4:6329117..6329235 25.723 WFS1|Wolfram syndrome 1 (wolframin) -57550 (+) PPP2R2C|protein phosphatase 2, regulatory subunit B, gamma 54408 (-)

10:1.000

chr7:5603327..5603445 24.519 ACTB|actin, beta -33177 (-) FSCN1|fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) 29052 (+)

-3:0.993

chr3:113007036..113007155 24.287 BOC|Boc homolog (mouse) -75696 (+) WDR52|WD repeat domain 52 153244 (-)

4:0.259

chr16:88509554..88509666 23.624 ZNF469|zinc finger protein 469 -15732 (+) ZFPM1|zinc finger protein, multitype 1 10095 (+)

-13:1.000

chr17:80739793..80739913 23.421 TBCD|tubulin folding cofactor D -29805 (+) ZNF750|zinc finger protein 750 58056 (-)

-16:1.000

chr19:18107755..18107886 23.331 KCNN1|potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 -45710 (+) ARRDC2|arrestin domain containing 2 4130 (+)

11:1.000

chr1:999732..999912 23.300 LOC100288175|uncharacterized LOC100288175 -4710 (+) RNF223|ring finger protein 223 9864 (-)

chr15:22436192..22436316 23.003 OR4N4|olfactory receptor, family 4, subfamily N, member 4 -53809 (+) 36968 (-)

-31:0.998

chr17:6955494..6955633 22.953 SLC16A11|solute carrier family 16, member 11 (monocarboxylic acid transporter 11) -8322 (-) CLEC10A|C-type lectin domain family 10, member A 27988 (-)

-11:0.410

chr17:71251955..71252088 22.935 C17orf80|chromosome 17 open reading frame 80 -22631 (+) CPSF4L|cleavage and polyadenylation specific factor 4-like 5997 (-)

-20:1.000

chr22:50468825..50468943 22.836 IL17REL|interleukin 17 receptor E-like -17814 (-) MLC1|megalencephalic leukoencephalopathy with subcortical cysts 1 54808 (-)

8:0.790

chr17:29764425..29764553 22.755 RAB11FIP4|RAB11 family interacting protein 4 (class II) -45625 (+) RAB11FIP4|RAB11 family interacting protein 4 (class II) 50572 (+)

chr8:37773819..37773947 22.711 RAB11FIP1|RAB11 family interacting protein 1 (class I) -16882 (-) GOT1L1|glutamic-oxaloacetic transaminase 1-like 1 23763 (-)

chr16:85855151..85855300 22.628 COX4I1|cytochrome c oxidase subunit IV isoform 1 -21890 (+) IRF8|interferon regulatory factor 8 77561 (+)

-50:0.981

chr1:999395..999575 22.589 LOC100288175|uncharacterized LOC100288175 -4373 (+) RNF223|ring finger protein 223 10201 (-)

chr7:142705138..142705264 22.502 KEL|Kell blood group, metallo-endopeptidase -45744 (-) OR9A2|olfactory receptor, family 9, subfamily A, member 2 19048 (-)

-9:0.994

chr3:50230164..50230288 22.491 GNAT1|guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 -1136 (+) SLC38A3|solute carrier family 38, member 3 12480 (+)

-5:0.773

chr17:75491107..75491236 22.450 SEPT9|septin 9 -19847 (+) LOC100507351|uncharacterized LOC100507351 51849 (+)

32:0.977

chr11:130731969..130732093 22.382 ADAMTS15|ADAM metallopeptidase with thrombospondin type 1 motif, 15 -413369 (+) SNX19|sorting nexin 19 54314 (-)

-18:0.955, 36:0.987

chr14:21560769..21560885 22.345 ARHGEF40|Rho guanine nucleotide exchange factor (GEF) 40 -22393 (+) ZNF219|zinc finger protein 219 5675 (-)

-26:0.691

chr1:23964023..23964150 22.314 ID3|inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -77802 (-) RPL11|ribosomal protein L11 54194 (+)

12:1.000

chr16:87812817..87812945 22.267 KLHDC4|kelch domain containing 4 -13311 (-) SLC7A5|solute carrier family 7 (amino acid transporter light chain, L system), member 5 90194 (-)

-23:0.945

chr12:53278721..53278846 22.190 KRT78|keratin 78 -36037 (-) KRT8|keratin 8 20033 (-)

-13:0.998

chr22:23301493..23301624 22.105 IGLC1|immunoglobulin lambda constant 1 (Mcg marker) IGLL5|immunoglobulin lambda-like polypeptide 5 -71475 (+) GNAZ|guanine nucleotide binding protein (G protein), alpha z polypeptide 110958 (+)

20:0.999

chr6:170231878..170232005 22.094 C6orf70|chromosome 6 open reading frame 70 -80219 (+) DLL1|delta-like 1 (Drosophila) 367733 (-)

-22:0.232

chr15:45722556..45722688 21.948 SPATA5L1|spermatogenesis associated 5-like 1 -28070 (+) C15orf48|chromosome 15 open reading frame 48 175 (+)

-18:0.613, 36:0.996

chr10:45428277..45428406 21.947 TMEM72|transmembrane protein 72 -21623 (+) TMEM72-AS1|TMEM72 antisense RNA 1 (non-protein coding) 26806 (-)

-18:0.993

chr7:75943709..75943831 21.933 HSPB1|heat shock 27kDa protein 1 -10716 (+) YWHAG|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 44428 (-)

36:0.919, -39:0.992

chr1:225662753..225662885 21.931 LBR|lamin B receptor -46263 (-) ENAH|enabled homolog (Drosophila) 177968 (-)

-20:0.998, 32:0.917

chr11:33879524..33879644 21.831 FBXO3|F-box protein 3 -83592 (-) LMO2|LIM domain only 2 (rhombotin-like 1) 11458 (-)

-4:0.999

chr9:139014852..139014976 21.801 C9orf69|chromosome 9 open reading frame 69 -4185 (-) LHX3|LIM homeobox 3 80074 (-)

15:0.996

chr4:3445304..3445427 21.758 HGFAC|HGF activator -1657 (+) DOK7|docking protein 7 19702 (+)

8:0.467

chr6:110026511..110026649 21.730 FIG4|FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae) -14056 (+) GPR6|G protein-coupled receptor 6 273676 (+)

-37:1.000

chr17:41837860..41837992 21.694 SOST|sclerostin -1783 (-) DUSP3|dual specificity phosphatase 3 18358 (-)

35:0.996, -38:0.309

chr15:42103708..42103833 21.691 MAPKBP1|mitogen-activated protein kinase binding protein 1 -36932 (+) JMJD7-PLA2G4B|JMJD7-PLA2G4B readthrough JMJD7|jumonji domain containing 7 16488 (+)

19:0.568

chr12:123344917..123345027 21.689 HIP1R|huntingtin interacting protein 1 related -24919 (+) 35643 (-)

-3:1.000

chr16:57683052..57683175 21.669 GPR56|G protein-coupled receptor 56 -9796 (+) GPR97|G protein-coupled receptor 97 19094 (+)

-5:0.986, 37:0.326

chr15:78400776..78400902 21.655 SH2D7|SH2 domain containing 7 -15913 (+) CIB2|calcium and integrin binding family member 2 22923 (-)

24:1.000

chr15:40567013..40567130 21.643 PAK6|p21 protein (Cdc42/Rac)-activated kinase 6 -21705 (+) ANKRD63|ankyrin repeat domain 63 7715 (-)

-20:0.990, 21:1.000

chr16:68544195..68544308 21.560 SMPD3|sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) -61770 (-) ZFP90|zinc finger protein 90 homolog (mouse) 19782 (+)

0:0.988

chr22:20960618..20960741 21.555 MED15|mediator complex subunit 15 -41855 (+) PI4KA|phosphatidylinositol 4-kinase, catalytic, alpha 128275 (-)

-6:0.697

chr9:129961617..129961751 21.555 ANGPTL2|angiopoietin-like 2 -76654 (-) GARNL3|GTPase activating Rap/RanGAP domain-like 3 65123 (+)

chr17:40474901..40475028 21.548 STAT5A|signal transducer and activator of transcription 5A -34439 (+) STAT3|signal transducer and activator of transcription 3 (acute-phase response factor) 65450 (-)

-26:0.999

chr4:173946354..173946484 21.528 GALNTL6|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 -1211775 (+) GALNT7|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) 143533 (+)

-6:0.634

chr11:68868992..68869130 21.519 -11535 (+) MYEOV|myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas) 192561 (+)

-19:0.965

chr7:1032885..1033022 21.508 CYP2W1|cytochrome P450, family 2, subfamily W, polypeptide 1 -9984 (+) C7orf50|chromosome 7 open reading frame 50 35004 (-)

22:0.967

chr12:50038458..50038574 21.505 PRPF40B|PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) -14190 (+) 62494 (-)

-7:1.000

chr10:72309755..72309883 21.497 KIAA1274|KIAA1274 -71204 (+) PRF1|perforin 1 (pore forming protein) 52650 (-)

-16:0.999

chr7:3194636..3194759 21.488 CARD11|caspase recruitment domain family, member 11 -111235 (-) SDK1|sidekick cell adhesion molecule 1 146302 (+)

18:0.798

chr12:115100561..115100649 21.478 TBX5|T-box 5 -254387 (-) TBX3|T-box 3 21535 (-)

-19:0.998

chr1:6306895..6307036 21.436 HES3|hairy and enhancer of split 3 (Drosophila) -2714 (+) GPR153|G protein-coupled receptor 153 14118 (-)

-9:0.998

chr6:136231046..136231177 21.376 PDE7B|phosphodiesterase 7B -58260 (+) FAM54A|family with sequence similarity 54, member A 340318 (-)

-1:0.852

chr10:102193636..102193780 21.354 LINC00263|long intergenic non-protein coding RNA 263 -60080 (+) WNT8B|wingless-type MMTV integration site family, member 8B 29097 (+)

-27:0.913, 60:0.211

chr8:142441682..142441808 21.335 PTP4A3|protein tyrosine phosphatase type IVA, member 3 -9684 (+) FLJ43860|FLJ43860 protein 75572 (-)

3:1.000

chr3:46530302..46530435 21.323 LTF|lactotransferrin -23871 (-) RTP3|receptor (chemosensory) transporter protein 3 9150 (+)

-31:0.627, 32:0.645

chr11:63246422..63246552 21.315 SLC22A9|solute carrier family 22 (organic anion transporter), member 9 -109093 (+) HRASLS5|HRAS-like suppressor family, member 5 12057 (-)

-20:0.924

chr9:36555943..36556059 21.202 RNF38|ring finger protein 38 -154826 (-) MELK|maternal embryonic leucine zipper kinase 16923 (+)

14:0.268, 15:0.681

chr2:127285799..127285926 21.127 CNTNAP5|contactin associated protein-like 5 -2502998 (+) GYPC|glycophorin C (Gerbich blood group) 127845 (+)

-6:0.977

chr11:60897350..60897481 21.117 CD5|CD5 molecule -27436 (+) VPS37C|vacuolar protein sorting 37 homolog C (S. cerevisiae) 31515 (-)

18:0.201, -31:0.799

chr7:73482295..73482401 21.096 ELN|elastin -39847 (+) LIMK1|LIM domain kinase 1 15778 (+)

-5:0.991

chr7:98062774..98062867 21.068 BAIAP2L1|BAI1-associated protein 2-like 1 -32387 (-) NPTX2|neuronal pentraxin II 183916 (+)

-17:0.744

chr17:61996713..61996847 21.063 GH1|growth hormone 1 -614 (-) CD79B|CD79b molecule, immunoglobulin-associated beta 12886 (-)

-23:0.371

chr22:45131837..45131967 21.060 PRR5-ARHGAP8|PRR5-ARHGAP8 readthrough PRR5|proline rich 5 (renal) -33649 (+) ARHGAP8|Rho GTPase activating protein 8 16559 (+)

5:0.999

chr5:133519993..133520099 21.041 SKP1|S-phase kinase-associated protein 1 -7364 (-) PPP2CA|protein phosphatase 2, catalytic subunit, alpha isozyme 41598 (-)

-5:0.993

chr8:28277132..28277277 21.038 ZNF395|zinc finger protein 395 -33243 (-) FBXO16|F-box protein 16 ZNF395|zinc finger protein 395 70575 (-)

20:0.931

chr12:53746511..53746645 21.015 SP7|Sp7 transcription factor -16575 (-) SP1|Sp1 transcription factor 27412 (+)

-14:0.988

chr22:41799923..41800060 21.014 TEF|thyrotrophic embryonic factor -21963 (+) TOB2|transducer of ERBB2, 2 42464 (-)

-10:0.993

chr17:74275674..74275791 20.956 FAM100B|family with sequence similarity 100, member B -14225 (+) QRICH2|glutamine rich 2 27938 (-)

16:0.999

chr18:74695380..74695499 20.941 MBP|myelin basic protein -3409 (-) MBP|myelin basic protein 33317 (-)

-4:0.999

chr11:119979019..119979141 20.921 PVRL1|poliovirus receptor-related 1 (herpesvirus entry mediator C) -379698 (-) TRIM29|tripartite motif containing 29 20466 (-)

10:0.955

chr17:61502907..61503019 20.892 TANC2|tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -231602 (+) CYB561|cytochrome b-561 15227 (-)

-26:0.982

chr2:113484386..113484508 20.856 SLC20A1|solute carrier family 20 (phosphate transporter), member 1 -80927 (+) CKAP2L|cytoskeleton associated protein 2-like 37775 (-)

32:1.000

chr8:42547760..42547891 20.853 SLC20A2|solute carrier family 20 (phosphate transporter), member 2 -150764 (-) CHRNB3|cholinergic receptor, nicotinic, beta 3 4800 (+)

-11:0.999

chr17:4316574..4316719 20.851 UBE2G1|ubiquitin-conjugating enzyme E2G 1 -46738 (-) SPNS3|spinster homolog 3 (Drosophila) 20596 (+)

28:1.000

chr14:70494632..70494767 20.850 SMOC1|SPARC related modular calcium binding 1 -148570 (+) SLC8A3|solute carrier family 8 (sodium/calcium exchanger), member 3 52193 (-)

16:0.998

chr1:17563650..17563771 20.818 PADI1|peptidyl arginine deiminase, type I -32045 (+) PADI3|peptidyl arginine deiminase, type III 11889 (+)

14:1.000

chr17:29852470..29852598 20.742 RAB11FIP4|RAB11 family interacting protein 4 (class II) -37473 (+) C17orf79|chromosome 17 open reading frame 79 333737 (-)

15:0.991, 40:0.713

chr15:74731166..74731291 20.735 SEMA7A|semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) -4916 (-) UBL7|ubiquitin-like 7 (bone marrow stromal cell-derived) 22219 (-)

11:1.000

chr14:105442570..105442690 20.718 AHNAK2|AHNAK nucleoprotein 2 -5810 (-) AHNAK2|AHNAK nucleoprotein 2 2078 (-)

-8:1.000, 23:0.214

chr9:137335274..137335403 20.708 RXRA|retinoid X receptor, alpha -116938 (+) COL5A1|collagen, type V, alpha 1 198309 (+)

8:0.999

chr19:38826240..38826358 20.691 KCNK6|potassium channel, subfamily K, member 6 -15492 (+) CATSPERG|cation channel, sperm-associated, gamma 214 (+)

1:0.589

chr10:48427008..48427127 20.686 GDF2|growth differentiation factor 2 -10281 (-) GDF10|growth differentiation factor 10 12012 (-)

-17:0.500

chr2:238421532..238421657 20.664 MLPH|melanophilin -25698 (+) PRLH|prolactin releasing hormone 53622 (+)

-21:0.985

chr15:75063531..75063648 20.635 CYP1A2|cytochrome P450, family 1, subfamily A, polypeptide 2 -22397 (+) CSK|c-src tyrosine kinase 10836 (+)

-4:0.995

chr19:43951307..43951425 20.617 TEX101|testis expressed 101 -32316 (+) LYPD3|LY6/PLAUR domain containing 3 18410 (-)

-7:0.523

chr19:10691783..10691902 20.614 CDKN2D|cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) -12204 (-) AP1M2|adaptor-related protein complex 1, mu 2 subunit 6106 (-)

chr16:30996380..30996503 20.596 -26904 (+) HSD3B7|hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 88 (+)

0:0.982

chr2:10575179..10575293 20.579 HPCAL1|hippocalcin-like 1 -131411 (+) ODC1|ornithine decarboxylase 1 13124 (-)

11:0.999

chr15:94867564..94867690 20.563 MCTP2|multiple C2 domains, transmembrane 2 -26166 (+) MCTP2|multiple C2 domains, transmembrane 2 31682 (+)

11:1.000

chr20:61640521..61640657 20.559 BHLHE23|basic helix-loop-helix family, member e23 -2203 (-) YTHDF1|YTH domain family, member 1 206934 (-)

9:0.999

chr11:2449571..2449690 20.502 TRPM5|transient receptor potential cation channel, subfamily M, member 5 -5373 (-) KCNQ1|potassium voltage-gated channel, KQT-like subfamily, member 1 16619 (+)

-15:1.000

chr1:205628178..205628299 20.480 ELK4|ELK4, ETS-domain protein (SRF accessory protein 1) -26239 (-) SLC45A3|solute carrier family 45, member 3 21330 (-)

chr16:67850550..67850682 20.468 TSNAXIP1|translin-associated factor X interacting protein 1 -9597 (+) CENPT|centromere protein T 17149 (-)

-18:1.000, 38:0.475, -69:0.213

chr3:42141381..42141508 20.467 TRAK1|trafficking protein, kinesin binding 1 -8611 (+) TRAK1|trafficking protein, kinesin binding 1 49304 (+)

27:0.932

chr1:155908078..155908205 20.461 KIAA0907|KIAA0907 -3939 (-) RXFP4|relaxin/insulin-like family peptide receptor 4 3348 (+)

-19:0.300

chr2:37641696..37641830 20.438 QPCT|glutaminyl-peptide cyclotransferase -69950 (+) CDC42EP3|CDC42 effector protein (Rho GTPase binding) 3 257016 (-)

chr14:23590118..23590258 20.431 CEBPE|CCAAT/enhancer binding protein (C/EBP), epsilon -1369 (-) SLC7A8|solute carrier family 7 (amino acid transporter light chain, L system), member 8 33373 (-)

32:0.998, -35:1.000

chr1:26471717..26471849 20.401 PDIK1L|PDLIM1 interacting kinase 1 like -33444 (+) FAM110D|family with sequence similarity 110, member D 13757 (+)

4:0.995

chr17:41771886..41772005 20.400 MEOX1|mesenchyme homeobox 1 -32670 (-) SOST|sclerostin 64198 (-)

chr1:46502847..46502967 20.367 MAST2|microtubule associated serine/threonine kinase 2 -123645 (+) PIK3R3|phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 95571 (-)

-4:1.000

chr17:47472509..47472614 20.357 ZNF652|zinc finger protein 652 -32981 (-) PHB|prohibitin 19654 (-)

4:1.000

chr8:71446790..71446930 20.354 NCOA2|nuclear receptor coactivator 2 -130834 (-) TRAM1|translocation associated membrane protein 1 73662 (-)

chr22:20144654..20144767 20.349 LOC388849|uncharacterized LOC388849 -7280 (-) RTN4R|reticulon 4 receptor 111057 (-)

-11:1.000

chr2:238480737..238480864 20.341 PRLH|prolactin releasing hormone -5584 (+) RAB17|RAB17, member RAS oncogene family 18546 (-)

15:1.000

chr8:143528965..143529089 20.325 TSNARE1|t-SNARE domain containing 1 -44490 (-) BAI1|brain-specific angiogenesis inhibitor 1 16349 (+)

3:0.999

chr7:48149870..48149999 20.323 UPP1|uridine phosphorylase 1 -20979 (+) ABCA13|ATP-binding cassette, sub-family A (ABC1), member 13 61121 (+)

8:1.000

chr1:9515939..9516083 20.321 -100065 (+) SLC25A33|solute carrier family 25, member 33 83521 (+)

11:0.767

chr1:29208690..29208822 20.302 OPRD1|opioid receptor, delta 1 -70103 (+) EPB41|erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 4835 (+)

-22:0.986

chr20:32045109..32045238 20.294 SNTA1|syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) -13612 (-) CBFA2T2|core-binding factor, runt domain, alpha subunit 2; translocated to, 2 32663 (+)

-2:0.989

chr16:19897694..19897834 20.237 GPRC5B|G protein-coupled receptor, family C, group 5, member B -1600 (-) GPR139|G protein-coupled receptor 139 187323 (-)

2:0.900

chr20:34583044..34583167 20.222 C20orf152|chromosome 20 open reading frame 152 -26569 (+) LOC647979|uncharacterized LOC647979 55799 (-)

-2:0.938

chr19:16358539..16358665 20.212 AP1M1|adaptor-related protein complex 1, mu 1 subunit -49852 (+) KLF2|Kruppel-like factor 2 (lung) 77039 (+)

-9:0.998

chr7:36331195..36331319 20.208 EEPD1|endonuclease/exonuclease/phosphatase family domain containing 1 -138202 (+) KIAA0895|KIAA0895 75415 (-)

9:0.975

chr9:136859639..136859743 20.170 VAV2|vav 2 guanine nucleotide exchange factor -2245 (-) BRD3|bromodomain containing 3 73502 (-)

4:0.999

chr20:937211..937314 20.158 ANGPT4|angiopoietin 4 -40346 (-) RSPO4|R-spondin 4 45655 (-)

9:0.203

chr4:183859390..183859519 20.145 DCTD|dCMP deaminase -20820 (-) WWC2|WW and C2 domain containing 2 161024 (+)

-10:0.994

chr6:5143994..5144114 20.118 PPP1R3G|protein phosphatase 1, regulatory subunit 3G -58335 (+) LYRM4|LYR motif containing 4 116943 (-)

-10:0.999

chr19:42612798..42612907 20.115 ZNF574|zinc finger protein 574 -32486 (+) POU2F2|POU class 2 homeobox 2 23739 (-)

-28:0.335

chr10:85965474..85965592 20.107 CDHR1|cadherin-related family member 1 -11080 (+) LRIT2|leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 19780 (-)

chr11:117714822..117714955 20.104 FXYD2|FXYD domain containing ion transport regulator 2 -16122 (-) FXYD6|FXYD domain containing ion transport regulator 6 32501 (-)

-9:0.992

chr1:201377450..201377570 20.094 LAD1|ladinin 1 -8769 (-) TNNI1|troponin I type 1 (skeletal, slow) 13349 (-)

7:0.624

chr5:79387663..79387801 20.068 THBS4|thrombospondin 4 -56568 (+) SERINC5|serine incorporator 5 164153 (-)

-11:0.999

chr16:68834268..68834403 20.058 CDH1|cadherin 1, type 1, E-cadherin (epithelial) -63024 (+) TMCO7|transmembrane and coiled-coil domains 7 43170 (+)

chr3:45970645..45970769 20.051 CCR9|chemokine (C-C motif) receptor 9 -42652 (+) CXCR6|chemokine (C-X-C motif) receptor 6 14265 (+)

24:0.983

chr16:89233964..89234084 20.044 -20078 (+) CDH15|cadherin 15, type 1, M-cadherin (myotubule) 4175 (+)

24:0.920

chr2:98313854..98313966 20.038 ACTR1B|ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -33336 (-) ZAP70|zeta-chain (TCR) associated protein kinase 70kDa 16132 (+)

17:0.996

chr11:36768751..36768877 20.031 RAG2|recombination activating gene 2 -149012 (-) LRRC4C|leucine rich repeat containing 4C 3545780 (-)

-34:0.994, 38:0.999

chr1:205242720..205242842 20.030 TMCC2|transmembrane and coiled-coil domain family 2 -6147 (+) NUAK2|NUAK family, SNF1-like kinase, 2 48062 (-)

-11:0.995

chr1:21695090..21695217 20.023 ECE1|endothelin converting enzyme 1 -23173 (-) NBPF3|neuroblastoma breakpoint family, member 3 71529 (+)

11:0.932

chr20:45901674..45901800 20.007 EYA2|eyes absent homolog 2 (Drosophila) -378185 (+) ZMYND8|zinc finger, MYND-type containing 8 25832 (-)

-8:0.993

chr17:26821858..26821987 19.998 SLC13A2|solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 -21216 (+) FOXN1|forkhead box N1 29036 (+)

-15:1.000

chr12:5131754..5131868 19.992 KCNA1|potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) -112751 (+) KCNA5|potassium voltage-gated channel, shaker-related subfamily, member 5 21308 (+)

-7:0.935

chr3:58518597..58518717 19.987 KCTD6|potassium channel tetramerisation domain containing 6 -34566 (+) ACOX2|acyl-CoA oxidase 2, branched chain 4243 (-)

3:1.000

chr1:175288875..175289010 19.983 KIAA0040|KIAA0040 -126912 (-) TNR|tenascin R (restrictin, janusin) 423768 (-)

15:1.000

chr1:27611288..27611401 19.982 WDTC1|WD and tetratricopeptide repeats 1 -50182 (+) TMEM222|transmembrane protein 222 37307 (+)

4:0.966

chr20:1294278..1294404 19.971 SDCBP2|syndecan binding protein (syntenin) 2 -128 (-) LOC100507495|uncharacterized LOC100507495 11710 (+)

-19:0.997

chr3:127371134..127371274 19.956 PODXL2|podocalyxin-like 2 -23172 (+) ABTB1|ankyrin repeat and BTB (POZ) domain containing 1 20613 (+)

-11:0.887

chr1:20244627..20244753 19.950 -35727 (+) PLA2G2E|phospholipase A2, group IIE 5390 (-)

-10:0.983

chr20:31240825..31240949 19.943 C20orf203|chromosome 20 open reading frame 203 -1217 (-) COMMD7|COMM domain containing 7 90366 (-)

18:0.999

chr17:79075654..79075769 19.931 BAIAP2|BAI1-associated protein 2 -66706 (+) AATK|apoptosis-associated tyrosine kinase 30051 (-)

26:0.900, -104:0.319

chr16:10603528..10603674 19.929 ATF7IP2|activating transcription factor 7 interacting protein 2 -80861 (+) EMP2|epithelial membrane protein 2 70889 (-)

18:0.999

chr19:47940024..47940146 19.914 MEIS3|Meis homeobox 3 -17322 (-) SLC8A2|solute carrier family 8 (sodium/calcium exchanger), member 2 35062 (-)

-16:0.999

chr8:8130839..8130967 19.898 FLJ10661|family with sequence similarity 86, member A pseudogene -44761 (+) SGK223|homolog of rat pragma of Rnd2 44985 (-)

-12:0.988

chr11:34196012..34196109 19.852 NAT10|N-acetyltransferase 10 (GCN5-related) -68810 (+) ABTB2|ankyrin repeat and BTB (POZ) domain containing 2 183495 (-)

-6:0.893

chr1:108668262..108668384 19.848 VAV3|vav 3 guanine nucleotide exchange factor -160723 (-) SLC25A24|solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 67073 (-)

18:0.993

chr16:67678674..67678802 19.831 CTCF|CCCTC-binding factor (zinc finger protein) -82344 (+) RLTPR|RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing 288 (+)

25:0.365

chr11:46911302..46911424 19.824 CKAP5|cytoskeleton associated protein 5 -43510 (-) LRP4|low density lipoprotein receptor-related protein 4 28699 (-)

-15:0.987

chr14:94406115..94406244 19.797 FAM181A|family with sequence similarity 181, member A -12471 (+) ASB2|ankyrin repeat and SOCS box containing 2 17587 (-)

-20:0.985, 107:0.393

chr2:30929988..30930119 19.787 LCLAT1|lysocardiolipin acyltransferase 1 -259905 (+) CAPN13|calpain 13 100240 (-)

9:0.999

chr17:17763636..17763763 19.779 SREBF1|sterol regulatory element binding transcription factor 1 -23375 (-) TOM1L2|target of myb1-like 2 (chicken) 112042 (-)

10:0.990

chr3:127689938..127690066 19.773 KBTBD12|kelch repeat and BTB (POZ) domain containing 12 -48100 (+) SEC61A1|Sec61 alpha 1 subunit (S. cerevisiae) 81185 (+)

chr2:48647982..48648115 19.769 FOXN2|forkhead box N2 -106230 (+) PPP1R21|protein phosphatase 1, regulatory subunit 21 19924 (+)

7:0.959

chr5:173846668..173846798 19.761 HMP19|HMP19 protein -373981 (+) MSX2|msh homeobox 2 304879 (+)

-5:0.999

chr17:61556386..61556501 19.756 ACE|angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 -2015 (+) ACE|angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 5748 (+)

0:0.999

chr11:117924217..117924355 19.754 IL10RA|interleukin 10 receptor, alpha -66999 (+) TMPRSS4|transmembrane protease, serine 4 23457 (+)

11:1.000

chr14:68038113..68038240 19.732 PLEKHH1|pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 -38203 (+) PIGH|phosphatidylinositol glycan anchor biosynthesis, class H 28791 (-)

8:0.471

chr18:56448916..56449058 19.727 MALT1|mucosa associated lymphoid tissue lymphoma translocation gene 1 -110142 (+) ZNF532|zinc finger protein 532 81132 (+)

-12:1.000

chr19:10755564..10755672 19.719 SLC44A2|solute carrier family 44, member 2 -19399 (+) LOC147727|uncharacterized LOC147727 8893 (-)

13:0.635

chr1:17452381..17452512 19.703 PADI2|peptidyl arginine deiminase, type II -6539 (-) PADI1|peptidyl arginine deiminase, type I 79219 (+)

-17:0.998

chr1:36565328..36565448 19.691 ADPRHL2|ADP-ribosylhydrolase like 2 -10910 (+) COL8A2|collagen, type VIII, alpha 2 461 (-)

-6:1.000

chr1:9927653..9927778 19.674 CLSTN1|calsyntenin 1 -43149 (-) CTNNBIP1|catenin, beta interacting protein 1 42594 (-)

1:0.999

chr11:2326693..2326808 19.668 TSPAN32|tetraspanin 32 -3364 (+) CD81|CD81 molecule 71797 (+)

-8:0.997

chr17:74117614..74117774 19.658 EXOC7|exocyst complex component 7 -17829 (-) FOXJ1|forkhead box J1 19680 (-)

-10:0.853

chr15:42281850..42281973 19.647 EHD4|EH-domain containing 4 -17158 (-) PLA2G4E|phospholipase A2, group IVE 60989 (-)

-18:0.358

chr11:2440993..2441108 19.637 TSSC4|tumor suppressing subtransferable candidate 4 -17528 (+) TRPM5|transient receptor potential cation channel, subfamily M, member 5 3207 (-)

11:0.998

chr16:19097923..19098065 19.635 COQ7|coenzyme Q7 homolog, ubiquinone (yeast) -18729 (+) ITPRIPL2|inositol 1,4,5-trisphosphate receptor interacting protein-like 2 27254 (+)

-20:0.994

chr1:205225399..205225525 19.631 TMCC2|transmembrane and coiled-coil domain family 2 -27404 (+) TMCC2|transmembrane and coiled-coil domain family 2 11172 (+)

16:0.935

chr1:205626793..205626915 19.618 ELK4|ELK4, ETS-domain protein (SRF accessory protein 1) -24855 (-) SLC45A3|solute carrier family 45, member 3 22714 (-)

8:0.990

chr10:94194890..94194999 19.617 MARCH5|membrane-associated ring finger (C3HC4) 5 -143890 (+) IDE|insulin-degrading enzyme 62549 (-)

10:0.930

chr7:128731659..128731810 19.593 TNPO3|transportin 3 -36529 (-) SMO|smoothened, frizzled family receptor 96978 (+)

1:0.925

chr10:103989638..103989777 19.588 ELOVL3|ELOVL fatty acid elongase 3 -3565 (+) PITX3|paired-like homeodomain 3 11522 (-)

-12:0.977

chr11:1853790..1853933 19.576 CTSD|cathepsin D -68626 (-) SYT8|synaptotagmin VIII 1856 (+)

-7:1.000

chr21:47240590..47240704 19.574 PCBP3|poly(rC) binding protein 3 -177018 (+) PCBP3|poly(rC) binding protein 3 29241 (+)

16:0.996

chr3:52178410..52178533 19.567 DUSP7|dual specificity phosphatase 7 -88196 (-) POC1A|POC1 centriolar protein homolog A (Chlamydomonas) 9959 (-)

10:0.953

chr11:61103803..61103929 19.556 DAK|dihydroxyacetone kinase 2 homolog (S. cerevisiae) -1774 (+) CYBASC3|cytochrome b, ascorbate dependent 3 20425 (-)

-3:0.999

chr10:115559479..115559613 19.553 C10orf81|chromosome 10 open reading frame 81 -34969 (+) DCLRE1A|DNA cross-link repair 1A 54370 (-)

-5:0.999

chr8:94834666..94834802 19.553 TMEM67|transmembrane protein 67 -67620 (+) PDP1|pyruvate dehyrogenase phosphatase catalytic subunit 1 94446 (+)

-9:0.993

chr12:1762105..1762219 19.544 WNT5B|wingless-type MMTV integration site family, member 5B -23751 (+) ADIPOR2|adiponectin receptor 2 38004 (+)

chr1:41882877..41882997 19.543 SCMH1|sex comb on midleg homolog 1 (Drosophila) -175101 (-) EDN2|endothelin 2 67382 (-)

2:1.000

chr9:37913732..37913883 19.531 MCART1|mitochondrial carrier triple repeat 1 -9441 (-) SHB|Src homology 2 domain containing adaptor protein B 155334 (-)

-30:0.231, 86:0.410

chr17:48919337..48919455 19.524 WFIKKN2|WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 -6792 (+) TOB1|transducer of ERBB2, 1 24300 (-)

13:0.971

chr6:37659901..37660026 19.512 CCDC167|coiled-coil domain containing 167 -192267 (-) MDGA1|MAM domain containing glycosylphosphatidylinositol anchor 1 5743 (-)

4:0.987

chr3:148991016..148991157 19.496 CP|ceruloplasmin (ferroxidase) -51279 (-) TM4SF18|transmembrane 4 L six family member 18 60316 (-)

-18:0.943, 36:0.501

chr17:20224214..20224339 19.490 SPECC1|sperm antigen with calponin homology and coiled-coil domains 1 -115842 (+) CCDC144C|coiled-coil domain containing 144C 190 (+)

22:0.999, -25:0.999

chr7:5125182..5125303 19.489 RBAK-LOC389458|RBAK-LOC389458 readthrough RBAK|RB-associated KRAB zinc finger -39741 (+) WIPI2|WD repeat domain, phosphoinositide interacting 2 104587 (+)

7:0.999

chr1:206757114..206757249 19.488 RASSF5|Ras association (RalGDS/AF-6) domain family member 5 -26284 (+) EIF2D|eukaryotic translation initiation factor 2D 28574 (-)

8:0.999

chr16:23193808..23193924 19.487 USP31|ubiquitin specific peptidase 31 -33317 (-) SCNN1G|sodium channel, nonvoltage-gated 1, gamma 186 (+)

chr1:165897461..165897582 19.461 UCK2|uridine-cytidine kinase 2 -100435 (+) FAM78B|family with sequence similarity 78, member B 238433 (-)

-3:0.737

chr15:43517789..43517919 19.457 EPB42|erythrocyte membrane protein band 4.2 -4576 (-) TGM5|transglutaminase 5 41200 (-)

-10:0.842

chr16:22012428..22012561 19.455 PDZD9|PDZ domain containing 9 -66 (-) C16orf52|chromosome 16 open reading frame 52 6994 (+)

-11:0.999

chr9:139383199..139383328 19.420 SEC16A|SEC16 homolog A (S. cerevisiae) -5021 (-) NOTCH1|notch 1 56987 (-)

0:0.994

chr1:200457928..200458061 19.397 ZNF281|zinc finger protein 281 -78800 (-) KIF14|kinesin family member 14 131885 (-)

13:0.890

chr21:35296446..35296582 19.385 ATP5O|ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -8422 (-) MRPS6|mitochondrial ribosomal protein S6 SLC5A3|solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 149327 (+)

-26:0.946

chr13:27559566..27559703 19.375 GPR12|G protein-coupled receptor 12 -224781 (-) USP12|ubiquitin specific peptidase 12 186227 (-)

-23:0.885

chr1:248100341..248100477 19.368 OR2T8|olfactory receptor, family 2, subfamily T, member 8 -16090 (+) OR2L13|olfactory receptor, family 2, subfamily L, member 13 83 (+)

26:0.970, -69:0.998

chr9:33722223..33722338 19.367 ANXA2P2|annexin A2 pseudogene 2 -98062 (+) PRSS3|protease, serine, 3 28360 (+)

23:0.546, -29:0.998

chr9:71199475..71199609 19.336 C9orf71|chromosome 9 open reading frame 71 -43777 (-) PIP5K1B|phosphatidylinositol-4-phosphate 5-kinase, type I, beta 120834 (+)

-30:0.997, 42:0.973

chr14:72219880..72220016 19.335 SIPA1L1|signal-induced proliferation-associated 1 like 1 -223907 (+) RGS6|regulator of G-protein signaling 6 178868 (+)

18:0.969

chr2:9954085..9954222 19.331 YWHAQ|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide -183028 (-) TAF1B|TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 29467 (+)

-8:0.983

chr17:72954122..72954238 19.327 OTOP3|otopetrin 3 -22286 (+) 14574 (-)

16:0.934

Examples of peaks fitted within regions

Complementary Motifs Enriched In Peaks:

Motif Name

Sequence Logo

Motif Ensemble Enrichment (Motif Ensemble log-Likelihood Ratio)

Enrichment (log-Likelihood Ratio)

Precision and Recall

Prediction - Observation Correlation

Enrichment at Binding Sites

Number of Positively Predicted Peaks

CTCF.p2 81.398 (2199.673) 81.398 (2199.673) 0.9491 0.4879 5.2811 25428/44017

Contribution and Correlation Plots

Top Motifs Enriched In Peaks:

Motif Name

Sequence Logo

Enrichment (log-Likelihood Ratio)

Precision and Recall

Prediction - Observation Correlation

Enrichment at Binding Sites

Number of Positively Predicted Peaks

CTCF.p2 81.398 (2199.673) 0.9491 0.4879 5.2811 25428/44017
denovo_WM_21 58.44 (2034.002) 0.9418 0.4793 5.3316 24117/44017
denovo_WM_17 52.368 (1979.144) 0.9236 0.4473 5.2711 22675/44017
JASPAR.CTCF.wm 36.242 (1795.106) 0.9505 0.4939 4.7093 30151/44017
HTSELEX.CTCF.C2H2.full.monomeric.wm1 22.951 (1566.682) 0.8098 0.3488 5.8104 13757/44017
denovo_WM_22 22.84 (1564.257) 0.9325 0.4698 4.3159 30640/44017
denovo_WM_18 22.252 (1551.224) 0.9328 0.4681 4.2874 30714/44017
HCMC.CTCF_f2.wm 18.661 (1463.228) 0.9403 0.4756 4.218 32154/44017
denovo_WM_5 10.995 (1198.723) 0.8173 0.4123 3.7859 27102/44017
denovo_WM_24 10.215 (1161.933) 0.8914 0.414 3.258 35342/44017

Downloads

SMC3 Replicate 1

SMC3 Replicate 2

BG Replicate 1

BG Replicate 2